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Nutrients 2017, 9(9), 996;

Weight Management Interventions in Women with and without PCOS: A Systematic Review

Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska academy, University of Gothenburg, Box 430, 405 30 Gothenburg, Sweden
Department of Obstetrics and Gyneacology, NU Hospital Groups, Lärketorpsvägen 4, 461 73 Trollhättan, Sweden
Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Locked Bag 29, Clayton, VIC 3168, Australia
Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
Monash Partners Academic Health Sciences Centre, Locked Bag 29, Clayton, VIC 3168, Australia
Robinson Research Institute, School of Paediatrics and Reproductive Health, University of Adelaide, 55 King William Street, North Adelaide, SA 5006, Australia
Author to whom correspondence should be addressed.
Received: 18 July 2017 / Revised: 28 August 2017 / Accepted: 5 September 2017 / Published: 8 September 2017
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Polycystic ovary syndrome (PCOS) is a common endocrinopathy among women associated with reproductive, metabolic and psychological features. While weight management is recommended as first-line treatment, it is unclear if women with PCOS achieve similar benefits as women without PCOS. This systematic review thus aimed to compare the efficacy of weight management interventions in women with and without PCOS. Databases were searched until May 2017. The primary outcome was weight and anthropometric, reproductive, metabolic and psychological measures were secondary outcomes. Of 3264 articles identified, 14 studies involving n = 933 (n = 9 high and n = 5 moderate risk of bias) met the inclusion criteria. No statistically significant differences in weight or weight loss following the intervention were found between women with and without PCOS in five studies, with the remaining studies not comparing the difference in weight or weight loss between these groups. Secondary outcomes did not differ significantly between the two groups. This review identified that there is a paucity of high quality research in this area and that more rigorous research is needed. View Full-Text
Keywords: polycystic ovary syndrome; obesity; insulin resistance; weight loss; systematic review polycystic ovary syndrome; obesity; insulin resistance; weight loss; systematic review

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Kataoka, J.; Tassone, E.C.; Misso, M.; Joham, A.E.; Stener-Victorin, E.; Teede, H.; Moran, L.J. Weight Management Interventions in Women with and without PCOS: A Systematic Review. Nutrients 2017, 9, 996.

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