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Nutrients 2017, 9(4), 388;

Parenteral Nutrition and Lipids

Faculty of Medicine, University of Calgary, G055 3330 Hospital Drive, Calgary, AB T2N 4N1, Canada
Alberta Health Services, Seventh Street Plaza, 14th Floor, North Tower, 10030–107 Street NW, Edmonton, AB T5J 3E4, Canada
Division of Gastroenterology, Royal Alexandra Hospital, University of Alberta, Edmonton, AB T5H 3V9, Canada
Author to whom correspondence should be addressed.
Received: 4 March 2017 / Revised: 25 March 2017 / Accepted: 10 April 2017 / Published: 14 April 2017
(This article belongs to the Special Issue Parenteral Nutrition 2016)
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Lipids have multiple physiological roles that are biologically vital. Soybean oil lipid emulsions have been the mainstay of parenteral nutrition lipid formulations for decades in North America. Utilizing intravenous lipid emulsions in parenteral nutrition has minimized the dependence on dextrose as a major source of nonprotein calories and prevents the clinical consequences of essential fatty acid deficiency. Emerging literature has indicated that there are benefits to utilizing alternative lipids such as olive/soy-based formulations, and combination lipids such as soy/MCT/olive/fish oil, compared with soybean based lipids, as they have less inflammatory properties, are immune modulating, have higher antioxidant content, decrease risk of cholestasis, and improve clinical outcomes in certain subgroups of patients. The objective of this article is to review the history of IVLE, their composition, the different generations of widely available IVLE, the variables to consider when selecting lipids, and the complications of IVLE and how to minimize them. View Full-Text
Keywords: parenteral nutrition; lipids; intravenous Lipid Emulsions parenteral nutrition; lipids; intravenous Lipid Emulsions
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Raman, M.; Almutairdi, A.; Mulesa, L.; Alberda, C.; Beattie, C.; Gramlich, L. Parenteral Nutrition and Lipids. Nutrients 2017, 9, 388.

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