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Low Glycemic Index Prototype Isomaltulose—Update of Clinical Trials

1
Clinical Research Unit, Centre of Internal Medicine, Justus Liebig University, 35392 Giessen, Hesse, Germany
2
BENEO-Institute, 67283 Obrigheim/Pfalz, Germany
3
Applied Nutritional Science/Dietetics, University of Hohenheim, 70599 Stuttgart, Baden-Württemberg, Germany
*
Author to whom correspondence should be addressed.
Nutrients 2017, 9(4), 381; https://doi.org/10.3390/nu9040381
Received: 12 February 2017 / Revised: 5 April 2017 / Accepted: 12 April 2017 / Published: 13 April 2017
Low glycemic index diets are supposed to achieve a more beneficial effect on blood glucose control in people with diabetes mellitus and may also provide metabolic benefits for the general population. A prototype of a low-glycemic index carbohydrate is the natural occurring disaccharide isomaltulose that can be commercially produced from sucrose (beet sugar) to industrial scale. It is currently used in various food and drink applications as well as special and clinical nutrition feeds and formula diet as a food ingredient and alternative sugar. Here we provide an overview on clinical trials with isomaltulose including an analysis of its effects on glycemia and fat oxidation as compared to high glycemic index sugars and carbohydrates. In addition, we discuss recent reports on beneficial effects in weight-loss maintenance and pregnancy. View Full-Text
Keywords: glycemic index; isomaltulose; glucose metabolism; diabetes mellitus; weight-loss maintenance; clinical trials; fertility and pregnancy outcome; sweetened beverages glycemic index; isomaltulose; glucose metabolism; diabetes mellitus; weight-loss maintenance; clinical trials; fertility and pregnancy outcome; sweetened beverages
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Maresch, C.C.; Petry, S.F.; Theis, S.; Bosy-Westphal, A.; Linn, T. Low Glycemic Index Prototype Isomaltulose—Update of Clinical Trials. Nutrients 2017, 9, 381.

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