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Nutrients 2017, 9(10), 1133;

Stability of Commercially Available Macular Carotenoid Supplements in Oil and Powder Formulations

Nutrition Research Centre Ireland, School of Health Science, Carriganore House, Waterford Institute of Technology, West Campus, Waterford X91 K236, Ireland
Author to whom correspondence should be addressed.
Received: 8 September 2017 / Revised: 3 October 2017 / Accepted: 13 October 2017 / Published: 17 October 2017
(This article belongs to the Special Issue Dietary Supplements)
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We previously identified that the concentration of zeaxanthin in some commercially available carotenoid supplements did not agree with the product’s label claim. The conclusion of this previous work was that more quality assurance was needed to guarantee concordance between actual and declared concentrations of these nutrients i.e., lutein (L) zeaxanthin (Z) and meso-zeaxanthin (MZ) in commercially available supplements. Since this publication, we performed further analyses using different commercially available macular carotenoid supplements. Three capsules from one batch of eight products were analysed at two different time points. The results have been alarming. All of the powder filled products (n = 3) analysed failed to comply with their label claim (L: 19–74%; Z: 57–73%; MZ: 83–97%); however, the oil filled soft gel products (n = 5) met or were above their label claim (L: 98–122%; Z: 117–162%; MZ: 97–319%). We also identified that the carotenoid content of the oil filled capsules were stable over time (e.g., L average percentage change: −1.7%), but the powder filled supplements degraded over time (e.g., L average percentage change: −17.2%). These data are consistent with our previous work, and emphasize the importance of using carotenoid interventions in oil based formulas rather than powder filled formulas. View Full-Text
Keywords: macular carotenoid supplementation; lutein; zeaxanthin; meso-zeaxanthin; macular pigment macular carotenoid supplementation; lutein; zeaxanthin; meso-zeaxanthin; macular pigment

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Phelan, D.; Prado-Cabrero, A.; Nolan, J.M. Stability of Commercially Available Macular Carotenoid Supplements in Oil and Powder Formulations. Nutrients 2017, 9, 1133.

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