Next Article in Journal
Altered Skeletal Muscle Fatty Acid Handling in Subjects with Impaired Glucose Tolerance as Compared to Impaired Fasting Glucose
Previous Article in Journal
Anti-Diabetic Activities of Gastrodia elata Blume Water Extracts Are Mediated Mainly by Potentiating Glucose-Stimulated Insulin Secretion and Increasing β-Cell Mass in Non-Obese Type 2 Diabetic Animals

Micronutrients in Oncological Intervention

Akademie für Mikronährstoffmedizin, Essen, Zweigertstrasse 55, 45130 Essen, Germany
Interdisziplinäres onkologisches Zentrum (IOZ), München, Nußbaumstrasse 12, München 80336, Germany
Klinik Bad Trissl, Innere Medizin II-Onkologie und Komplementärmedizin, Oberaudorf 83080, Germany
St. Anna Hospital, Medizinische Klinik I, Herne, Hospitalstrasse 19, Herne 44649, Germany
Boston University Medical Center, 85 East Newton Street M-1033, Boston, MA 02118, USA
Klinik für Strahlentherapie und Radio-Onkologie, Ruhr Universität Bochum (RUB), Hölkeskampring 40, Herne 44625, Germany
Author to whom correspondence should be addressed.
Nutrients 2016, 8(3), 163;
Received: 23 November 2015 / Revised: 16 February 2016 / Accepted: 24 February 2016 / Published: 12 March 2016
Nutritional supplements are widely used among patients with cancer who perceive them to be anticancer and antitoxicity agents. Depending on the type of malignancy and the gender 30%–90% of the cancer patients supplement their diets with antioxidant and immuno-stabilizing micronutrients, such as selenium, vitamin C, and vitamin D, often without the knowledge of the treating physician. From the oncological viewpoint, there are justifiable concerns that dietary supplements decrease the effectiveness of chemotherapy and radiotherapy. Recent studies, however, have provided increasing evidence that treatment is tolerated better—with an increase in patient compliance and a lower rate of treatment discontinuations—when micronutrients, such as selenium, are added as appropriate to the patient’s medication. Nutritional supplementation tailored to an individual’s background diet, genetics, tumor histology, and treatments may yield benefits in subsets of patients. Clinicians should have an open dialogue with patients about nutritional supplements. Supplement advice needs to be individualized and come from a credible source, and it is best communicated by the physician. View Full-Text
Keywords: Micronutrients; antioxidants; vitamin D; selenium; l-carnitine; vitamin C; cancer; treatment related side effects; chemotherapy; radiotherapy Micronutrients; antioxidants; vitamin D; selenium; l-carnitine; vitamin C; cancer; treatment related side effects; chemotherapy; radiotherapy
Show Figures

Graphical abstract

MDPI and ACS Style

Gröber, U.; Holzhauer, P.; Kisters, K.; Holick, M.F.; Adamietz, I.A. Micronutrients in Oncological Intervention. Nutrients 2016, 8, 163.

AMA Style

Gröber U, Holzhauer P, Kisters K, Holick MF, Adamietz IA. Micronutrients in Oncological Intervention. Nutrients. 2016; 8(3):163.

Chicago/Turabian Style

Gröber, Uwe, Peter Holzhauer, Klaus Kisters, Michael F. Holick, and Irenäus A. Adamietz 2016. "Micronutrients in Oncological Intervention" Nutrients 8, no. 3: 163.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop