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Open AccessArticle

Could a Change in Diet Revitalize Children Who Suffer from Unresolved Fatigue?

University Medical Centre Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
Ziekenhuisgroep Twente, Hengelo, Geerdinksweg 141, 7555 DL Hengelo, The Netherlands
Author to whom correspondence should be addressed.
Nutrients 2015, 7(3), 1965-1977;
Received: 14 January 2015 / Revised: 16 February 2015 / Accepted: 11 March 2015 / Published: 13 March 2015
Many children deal with fatigue for which no proper treatment can be given. A possible explanation for their fatigue is a micro deficiency of minerals and vitamins. In this non-randomized controlled trial, we clinically evaluated symptoms of fatigue in children for whom a nutrient-rich diet was advised. A group of 98 children (2–18 years old) with unexplained symptoms of fatigue was examined. The dietary modifications consisted of green vegetables, beef, whole milk and full-fat butter. Children in the intervention group were asked to follow the diet for three months, whereas the control-group followed their normal diet. The primary outcome was symptoms of fatigue, as determined by a PedsQL Multidimensional Fatigue Scale, and secondary outcomes were compliance with the diet and BMI. Children, who followed the diet showed a significant decrease in the need to sleep (CI 0.83; 14.86, p = 0.03). They slept better through the night and took fewer naps. When analyzing components of the advised diet separately, a significant larger decrease in cognitive fatigue symptoms was seen for eating green vegetables according to the diet guidelines (CI 2.27; 30.63, p = 0.024). Furthermore, a lower need to sleep was seen when whole milk was consumed almost daily (CI 0.02; 14.62, p = 0.049). Our study showed that nutritional advice is an elegant, and effective method for decreasing some symptoms of medically unresolved fatigue in children. View Full-Text
Keywords: children; micronutrients; fatty acids; nutrient intake; fatigue; vegetables children; micronutrients; fatty acids; nutrient intake; fatigue; vegetables
MDPI and ACS Style

Steenbruggen, T.G.; Hoekstra, S.J.; Van der Gaag, E.J. Could a Change in Diet Revitalize Children Who Suffer from Unresolved Fatigue? Nutrients 2015, 7, 1965-1977.

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