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Microbiome Associations of Therapeutic Enteral Nutrition

1
Department of Internal Medicine, Section of Gastroenterology, Baylor College of Medicine, Houston, TX, 77030, USA
2
Department of Pediatrics, Section of Gastroenterology, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, 77030, USA
*
Author to whom correspondence should be addressed.
Nutrients 2014, 6(11), 5298-5311; https://doi.org/10.3390/nu6115298
Received: 21 August 2014 / Revised: 8 October 2014 / Accepted: 21 October 2014 / Published: 21 November 2014
(This article belongs to the Special Issue Recent Advances in Enteral Nutrition)
One of the most effective forms of therapeutic enteral nutrition is designated as “exclusive enteral nutrition” (EEN). EEN constitutes the monotonous enteral delivery of complete liquid nutrition and has been most explored in the treatment Crohn’s disease (CD), a form of inflammatory bowel disease. While EEN’s mechanisms of action are not clearly understood, it has been shown to modify the composition of the intestinal microbiome, an important component of CD pathogenesis. The current literature on the intestinal microbiome in healthy individuals and CD patients is reviewed with respect to EEN therapy. Further investigations in this field are needed to better understand the role and potential for EEN in chronic human disorders. View Full-Text
Keywords: enteral nutrition; Crohn’s disease; microbiota; IBD; rheumatoid arthritis enteral nutrition; Crohn’s disease; microbiota; IBD; rheumatoid arthritis
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Shah, R.; Kellermayer, R. Microbiome Associations of Therapeutic Enteral Nutrition. Nutrients 2014, 6, 5298-5311.

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