Green Tea Consumption Affects Cognitive Dysfunction in the Elderly: A Pilot Study
by
Kazuki Ide 1, Hiroshi Yamada 1,*, Norikata Takuma 2, Mijong Park 1, Noriko Wakamiya 1, Junpei Nakase 3, Yuuichi Ukawa 3 and Yuko M. Sagesaka 3
Kazuki Ide 1, Hiroshi Yamada 1,*, Norikata Takuma 2, Mijong Park 1, Noriko Wakamiya 1, Junpei Nakase 3, Yuuichi Ukawa 3 and Yuko M. Sagesaka 3
1
Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan
2
White Cross Nursing Home, 2-26-1 Suwa-cho, Higashimurayama, Tokyo 189-0021, Japan
3
Central Research Institute, ITO EN, Ltd., 21 Mekami, Makinohara, Shizuoka 421-0516, Japan
*
Author to whom correspondence should be addressed.
Nutrients 2014, 6(10), 4032-4042; https://doi.org/10.3390/nu6104032
Received: 10 May 2014 / Revised: 14 July 2014 / Accepted: 19 September 2014 / Published: 29 September 2014
Green tea is known to have various health benefits for humans. However, the effect of green tea consumption on cognitive dysfunction remains to be clinically verified. We conducted a clinical study to investigate the effects of green tea consumption on cognitive dysfunction. Twelve elderly nursing home residents with cognitive dysfunction (Mini-Mental State Examination Japanese version (MMSE-J) score: <28) participated in the study (2 men, 10 women; mean age, 88 years). The participants consumed green tea powder 2 g/day for 3 months. After three months of green tea consumption, the participants’ MMSE-J scores were significantly improved (before, 15.3 ± 7.7; after, 17.0 ± 8.2; p = 0.03). This result suggests that green tea consumption may be effective in improving cognitive function or reducing the progression of cognitive dysfunction; however, long-term large-scale controlled studies are needed to further clarify the effect.
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Keywords:
green tea; oral administration; cognitive function; elderly
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Ide, K.; Yamada, H.; Takuma, N.; Park, M.; Wakamiya, N.; Nakase, J.; Ukawa, Y.; Sagesaka, Y.M. Green Tea Consumption Affects Cognitive Dysfunction in the Elderly: A Pilot Study. Nutrients 2014, 6, 4032-4042.
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