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Standardised Parenteral Nutrition
Open AccessArticle

Developing and Implementing All-in-One Standard Paediatric Parenteral Nutrition

Department Gastroenterology, Great Ormond Street Hospital Foundation Trust, London, WC1N 3JH, UK
Hospital Pharmacy, University Hospital Basel, Basel 4031, Switzerland
Department Gastroenterology and Nutrition, University Children's Hospital Basel (UKBB), University of Basel, Basel 4056, Switzerland
Department Nutrition and Dietetics, University Hospital Basel, Basel 4031, Switzerland
Author to whom correspondence should be addressed.
Nutrients 2013, 5(6), 2006-2018;
Received: 10 January 2013 / Revised: 7 February 2013 / Accepted: 6 May 2013 / Published: 5 June 2013
(This article belongs to the Special Issue Parenteral Nutrition)
PDF [317 KB, uploaded 5 June 2013]


Parenteral nutrition (PN) is a feeding mode suitable for children that do not achieve requirements via the enteral route. For this intervention to be successful, healthcare professionals require: knowledge on nutrient requirements; access to an aseptic compounding facility; and a system that ensures adequate and safe delivery of PN. Previously, it was thought that individualised PN was the “gold standard” for delivering nutrients to children; however, studies have highlighted concerns regarding inadequate delivery of nutrients, prescribing and compounding errors. We, therefore, set out to develop and implement all-in-one (AIO) paediatric PN solutions. Through a systematic approach, four AIO PN solutions were developed: birth–two months of age (Ped 1); two months–10 kg (Ped 2); 11–15 kg (Ped 3); and 16–30 kg (Ped 4). We implemented them with the help of a teaching pack, over a one month time period, and reviewed usage at six months. At that time, five children initially received standard PN without electrolyte changes; but after a few days, electrolytes needed amendments, and three required individualised PN. A change to AIO PN is feasible and safe; however, some may require electrolyte changes, and there will always be those that will require individualised PN. View Full-Text
Keywords: parenteral nutrition; all-in-one parenteral nutrition; paediatrics; development; implementation parenteral nutrition; all-in-one parenteral nutrition; paediatrics; development; implementation

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Meyer, R.; Timmermann, M.; Schulzke, S.; Kiss, C.; Sidler, M.A.; Furlano, R.I. Developing and Implementing All-in-One Standard Paediatric Parenteral Nutrition. Nutrients 2013, 5, 2006-2018.

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