Next Article in Journal
Osteoporosis Prevention—A Worthy and Achievable Strategy
Next Article in Special Issue
Perceived Barriers to Application of Glycaemic Index: Valid Concerns or Lost in Translation?
Previous Article in Journal
Flavan-3-ol Compounds from Wine Wastes with in Vitro and in Vivo Antioxidant Activity
Previous Article in Special Issue
Changes in Intakes of Total and Added Sugar and their Contribution to Energy Intake in the U.S.
Open AccessArticle

Effect of the Glycemic Index of Carbohydrates on Acne vulgaris

Human Nutrition Unit, School of Molecular Bioscience G08, The University of Sydney, NSW 2006, Australia
Department of Dermatology, Concord Repatriation General Hospital, The University of Sydney, NSW 2006, Australia
Department of Statistics, Macquarie University, NSW 2109, Australia
Author to whom correspondence should be addressed.
Nutrients 2010, 2(10), 1060-1072;
Received: 3 September 2010 / Revised: 12 October 2010 / Accepted: 15 October 2010 / Published: 18 October 2010
(This article belongs to the Special Issue Carbohydrates)
Acne vulgaris may be improved by dietary factors that increase insulin sensitivity. We hypothesized that a low-glycemic index diet would improve facial acne severity and insulin sensitivity. Fifty-eight adolescent males (mean age ± standard deviation 16.5 ± 1.0 y and body mass index 23.1 ± 3.5 kg/m2) were alternately allocated to high or low glycemic index diets. Severity of inflammatory lesions on the face, insulin sensitivity (homeostasis modeling assessment of insulin resistance), androgens and insulin-like growth factor-1 and its binding proteins were assessed at baseline and at eight weeks, a period corresponding to the school term. Forty-three subjects (n = 23 low glycemic index and n = 20 high glycemic index) completed the study. Diets differed significantly in glycemic index (mean ± standard error of the mean, low glycemic index 51 ± 1 vs. high glycemic index 61 ± 2, p = 0.0002), but not in macronutrient distribution or fiber content. Facial acne improved on both diets (low glycemic index −26 ± 6%, p = 0.0004 and high glycemic index −16 ± 7%, p = 0.01), but differences between diets did not reach significance. Change in insulin sensitivity was not different between diets (low glycemic index 0.2 ± 0.1 and high glycemic index 0.1 ± 0.1, p = 0.60) and did not correlate with change in acne severity (Pearson correlation r = −0.196, p = 0.244). Longer time frames, greater reductions in glycemic load or/and weight loss may be necessary to detect improvements in acne among adolescent boys. View Full-Text
Keywords: glycemic index; carbohydrate; diet; acne vulgaris; adolescent males glycemic index; carbohydrate; diet; acne vulgaris; adolescent males
Show Figures

Graphical abstract

MDPI and ACS Style

Reynolds, R.C.; Lee, S.; Choi, J.Y.J.; Atkinson, F.S.; Stockmann, K.S.; Petocz, P.; Brand-Miller, J.C. Effect of the Glycemic Index of Carbohydrates on Acne vulgaris. Nutrients 2010, 2, 1060-1072.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

Only visits after 24 November 2015 are recorded.
Search more from Scilit
Back to TopTop