Traumatic Events and Post-Traumatic Stress Disorder in Adolescents with Severe Eating Disorder Admitted to a Day Care Hospital
Abstract
1. Introduction
2. Methods
2.1. Participants
2.2. Clinical and Sociodemographic Variables
2.3. Measures
- Child Depression Inventory, adapted to Spanish (CDI) [32,33]. The CDI is a 27-item self-report questionnaire which assesses affective, cognitive, and behavioural symptoms of depression. Each item consists of three statements graded in order to increase severity from 0 to 2. The cut-off point is 19. It has shown relatively high levels of internal consistency, retest reliability, and convergent validity.
- Eating Attitude Test, adapted to Spanish (EAT-40) [34,35]. The EAT-40 is a 40-item self-administered questionnaire with six possible answers ranging from ‘never’ to ‘always’. The total test score distinguishes between anorexic patients and the normal population, and between bulimics and the normal population. The Spanish version [34] has shown to achieve adequate sensitivity at a cut-off point of 20. It has also demonstrated good internal consistency.
- Early Trauma Inventory Self-Report Short Form (ETI-SR-SF) [36,37]. The ETI-SR-SF systematically assesses exposure to general trauma (11 items), physical abuse (5 items), emotional abuse (5 items), and sexual abuse (6 items). It has shown good internal consistency and psychometric properties in the Spanish adult population. The questionnaire offers two response options, one for minors and one for those over 18 years old. In our case, we only used the former, since our total sample is aged under 18. As the ETI-SR-SF is not validated in Spanish for the child and adolescent population, we used a cut-off point of 4 to evaluate the possible presence of PTSD following the validation in Spanish for an adult female population [36]. In doing to, we rely on previous findings that demonstrate that having endured at least four adverse childhood experiences (ACEs) is an important risk factor for many health conditions across the life span [38].
- Individual interview with a clinician to reach an agreement with the patient on which of the events marked in the ETI-SR-SF had been the most traumatic for them.
- Post-Traumatic Stress Disorder Symptom Severity Scale-Revised (EGSR) [39]. The EGSR is a 21-item structured interview based on DSM-5 criteria and is used to assess the severity of PTSD symptoms (re-experiencing; avoidance; cognitive and mood disturbances; hyperarousal). Patients should complete this questionnaire considering PTSD symptoms related to the traumatic event selected after the Phase 2 interview conducted with a clinician.
2.4. Data Analysis
3. Results
3.1. Participant’s Characteristics
3.2. Phase 1: Assessment of Depressive Symptoms, ED Symptoms, and Traumatic Events
3.3. Phase 2: Assessment of PTSD
3.4. Type of Traumatic Events Reported
3.5. Relationship Between PTSD and Severity of Disorder
4. Discussion
5. Conclusions
6. Limitations
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Peláez-Fernández, M.; Raich Escursell, R.; Labrador Encinas, F. Trastornos de la conducta alimentaria en España: Revisión de estudios epidemiológicos. Rev. Mex. Trastor. Aliment./Mex. J. Eat. Disord. 2010, 1, 62–75. [Google Scholar] [CrossRef]
- Hudson, J.; Hiripi, E.; Pope, H., Jr.; Kessler, R. The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication. Biol. Psychiatry 2007, 61, 348–358. [Google Scholar] [CrossRef]
- Smink, F.; Van Hoeken, D.; Hoek, H. Epidemiology, course and outcome of eating disorders. Curr. Opin. Psychiatry 2013, 26, 543–548. [Google Scholar] [CrossRef] [PubMed]
- Lindvall, D.; Wisting, L.; Oyyind, R. Feeding and eating disorders in the DSM-5 era: A systematic review of prevalence rates in non-clinical male and female samples. J. Eat. Disord. 2017, 5, 56. [Google Scholar] [CrossRef]
- Fairburn, C.G.; Harrison, P.J. Eating disorders. Lancet 2003, 361, 407–416. [Google Scholar] [CrossRef]
- Swanson, S.A.; Crow, S.J.; Le Grange, D.; Swendsen, J.; Merikangas, K.R. Prevalence and correlates of eating disorders in adolescents: Results from the national comorbidity survey replication adolescent supplement. Arch. Gen. Psychiatry 2011, 68, 714–723. [Google Scholar] [CrossRef]
- Yao, S.; Kuja-Halkola, R.; Thorton, L.M.; Runfola, C.D.; D’Onofrio, B.M.; Almqvist, C.; Lichtenstein, P.; Sjölander, A.; Larsson, H.; Bulik, C.M. Familial liability for eating disorders and suicide attempts: Evidence from a population registry in Sweden. JAMA Psychiatry 2016, 73, 284–291. [Google Scholar] [CrossRef]
- Treasure, J.; Duarte, T.A.; Schmidt, U. Eating disorders. Lancet 2020, 395, 899–911. [Google Scholar] [CrossRef] [PubMed]
- Millar, H.R.; Wardell, F.; Vyvyan, J.P.; Naji, S.A.; Prescott, G.J.; Eagles, J.M. Anorexia nervosa mortality in Northeast Scotland, 1965–1999. Am. J. Psychiatry 2005, 162, 753–757. [Google Scholar] [CrossRef]
- Cucchi, A.; Ryan, D.; Konstantakopoulos, G.; Stroumpa, S.; Kaçar, A.Ş.; Renshaw, S.; Landau, S.; Kravariti, E. Lifetime prevalence of non-suicidal self-injury in patients with eating disorders: A systematic review and meta-analysis. Psychol. Med. 2016, 46, 1345–1358. [Google Scholar] [CrossRef]
- Franko, D.L.; Keel, P.K. Suicidality in eating disorders: Occurrence, correlates, and clinical implications. Clin. Psychol. Rev. 2006, 26, 769–782. [Google Scholar] [CrossRef] [PubMed]
- Preti, A.; Rocchi, M.B.; Sisti, D.; Camboni, M.V.; Miotto, P. A comprehensive meta-analysis of the risk of suicide in eating disorders. Acta Psychiatr. Scand. 2011, 124, 6–17. [Google Scholar] [CrossRef] [PubMed]
- Mandelli, L.; Arminio, A.; Atti, A.R.; De Ronchi, D. Suicide attempts in eating disorder subtypes: A meta-analysis of the literature employing DSM-IV, DSM-5, or ICD-10 diagnostic criteria. Psychol. Med. 2019, 49, 1237–1249. [Google Scholar] [CrossRef]
- Sloan, G.; Leichner, P. Is there a relationship between sexual abuse or incest and eating disorders? Can. J. Psychiatry 1986, 31, 656–660. [Google Scholar] [CrossRef]
- Young, L. Sexual abuse and the problem of embodiment. Child Abus. Negl. 1992, 16, 89–100. [Google Scholar] [CrossRef]
- Tobin, D.L.; Molteni, A.L.; Elin, M.R. Early trauma, dissociation, and late onset in the eating disorders. Int. J. Eat. Disord. 1995, 17, 305–308. [Google Scholar] [CrossRef]
- Torem, M.S.; Curdue, K. PTSD presenting as an eating disorder. Stress Med. 1988, 4, 139–142. [Google Scholar] [CrossRef]
- Álvarez, M.J.; Masramom, H.; Foguet-Boreu, Q.; Tasa-Vinyals, E.; García-Eslava, J.S.; Roura-Poch, P.; Escoté-Llobet, S.; Gonzalez, A. Childhhood Trauma in Schizophrenia Spectrum Disorders: Dissociative, Psychotic Symptoms, and Suicide Behavior. J. Nerv. Ment. Dis. 2021, 209, 40–48. [Google Scholar] [CrossRef] [PubMed]
- Brewerton, T.D. Eating disorders, trauma, and comorbidity: Focus on PTSD. J. Treat. Prev. 2007, 15, 285–304. [Google Scholar] [CrossRef]
- Pignatelli, A.; Wampers, M.; Loriedo, C.; Biondi, M.; Vanderlinden, J. Childhood neglect in eating disorders: A systematic review and meta-analysis. J. Trauma Dissociat. 2017, 18, 100–115. [Google Scholar] [CrossRef]
- Mitchell, K.S.; Mazzeo, S.E.; Schlesinger, M.R.; Brewerton, T.D.; Smith, B.N. Comorbidity of partial and subthreshold PTSD among men and women with eating disorders in the National Comorbidity Survey-Replication Study. Int. J. Eat. Disord. 2012, 45, 307–315. [Google Scholar] [CrossRef] [PubMed]
- Mitchell, K.S.; Scioli, E.R.; Galovski, T.; Belfer, P.L.; Cooper, Z. Posttraumatic stress disorder and eating disorders: Maintaining mechanisms and treatment targets. Eat. Disord. 2021, 29, 292–306. [Google Scholar] [CrossRef] [PubMed]
- Reyes-Rodríguez, M.L.; Von Holle, A.; Ulman, T.F.; Thornton, L.M.; Klump, K.L.; Brandt, H.; Crawford, S.; Fichter, M.M.; Halmi, K.A.; Huber, T.; et al. Posttraumatic stress disorder in anorexia nervosa. Psychosom. Med. 2011, 73, 491–497. [Google Scholar] [CrossRef] [PubMed]
- Smolak, L.; Murnen, S. A meta-analytic examination of the relationship between child sexual abuse and eating disorders. Int. J. Eat. Disord. 2002, 31, 136–150. [Google Scholar] [CrossRef]
- Chen, L.; Murad, M.; Paras, M.; Colbenson, K.; Sattler, A.; Goranson, E.; Elamin, M.; Seime, R.; Shinozaki, G.; Prokop, L.; et al. Sexual abuse and lifetime diagnosis of psychiatric disorders: A systematic review and meta-analysis. Mayo Clin. Proc. 2010, 85, 618–629. [Google Scholar] [CrossRef]
- Caslini, M.; Bartoli, F.; Crocamo, C.; Dakanalis, A.; Clerici, M.; Carrà, G. Disentangling the association between child abuse and eating disorders: A systematic review and meta-analysis. Psychosom. Med. 2016, 78, 79–90. [Google Scholar] [CrossRef]
- Norman, R.E.; Byambaa, M.D.R.; Butchart, A.; Scott, J.; Vos, T. The Long-Term Health Consequences of Child Physical Abuse, Emotional Abuse, and Neglect: A Systematic Review and Meta-Analysis. PLoS Med. 2012, 9, e1001349. [Google Scholar] [CrossRef]
- Øverland Lie, S.; Ro, O.; Bang, L. Is bullying and teasing associated with eating disorders? A systematic review and meta-analysis. Int. J. Eat. Disord. 2019, 52, 497–514. [Google Scholar]
- Molendijk, M.; Hoek, H.; Brewerton, T.; Elzinga, B. Childhood maltreatment and eating disorder pathology: A systematic review and dose-response meta-analysis. Psychol. Med. 2017, 47, 1402. [Google Scholar] [CrossRef]
- Tagay, S.; Schlegl, S.; Senf, W. Traumatic events, posttraumatic stress symptomatology and somatoform symptoms in eating disorder patients. Eur. Eat. Disord. Rev. 2010, 18, 124–132. [Google Scholar] [CrossRef] [PubMed]
- American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th ed.; American Psychiatric Association: Washington, DC, USA, 2013. [Google Scholar]
- Del Barrio, V.; Roa, M.L.; Olmedo, M.; Colodrón, F. Primera adaptación del CDI-S a población española. Acción Psicol. 2002, 3, 263–272. [Google Scholar]
- Kovacs, M. The Children’s Depression Inventory. Psychopharmacol. Bull. 1985, 21, 995–998. [Google Scholar] [PubMed]
- Castro, J.; Toro, J.; Salamero, M.; Guimerá, E. The Eating Attitudes Test: Validation of the Spanish version. Psychol. Assess 1991, 7, 175–190. [Google Scholar]
- Garner, D.M.; Garfinkel, P.E. The Eating Attitudes Test: An index of the symptoms of anorexia nervosa. Psychol. Med. 1979, 9, 273–279. [Google Scholar] [CrossRef]
- Plaza, A.; Torres, A.; Martin-Santos, R.; Gelabert, E.; Imaz, M.L.; Navarro, P.; Bremner, J.D.; Valdes, M.; Garcia-Esteve, L. Validation and Test-Retest Reliability of Early Trauma Inventory in Spanish Postpartum Women. J. Nerv. Ment. Dis. 2011, 199, 280–285. [Google Scholar] [CrossRef]
- Bremner, J.D.; Bolus, R.; Mayer, E.A. Psychometric properties of the early trauma inventory-self report. J. Nerv. Ment. Dis. 2007, 195, 211–218. [Google Scholar] [CrossRef]
- Hughes, K.; Bellis, M.K.; Hardcastle, K.A.; Sethi, D.; Butchart, A.; Mikton, C.; Jones, L.; Dunne, M.P. The effect of multiple adverse childhood experiences on health: A systematic review and meta-analysis. Lancet Public Health 2017, 2, 356–366. [Google Scholar] [CrossRef]
- Echeburúa, E.; Amor, P.J.; Sarasua, B.; Zubizarreta, I.; Holgado-Tello, F.P.; Muñoz, J.M. Posttraumatic Stress Disorder Symptom Severity Scale-Revised (EGS-R) according to DSM-5 criteria: Psychometric Properties. Ter. Psicol. 2016, 34, 111–128. [Google Scholar] [CrossRef]
- Kong, S.; Bernstein, K. Childhood trauma as a predictor of eating psychopathology and its mediating variables in patients with eating disorders. J. Clin. Nurs. 2009, 18, 1897–1907. [Google Scholar] [CrossRef]
- Rodriguez, M.; Perez, V.; Garcia, Y. Impact of traumatic experiences and violent acts upon response to treatment of a sample of Colombian women with eating disorders. Int. J. Eat. Disord. 2005, 37, 299–306. [Google Scholar] [CrossRef]
- Kovács-Tóth, B.; Oláh, B.; Szabó, I.K.; Túry, F. Adverse childhood experiences increase the risk for eating disorders among adolescent. Front. Psychol. 2022, 1, 1063693. [Google Scholar] [CrossRef] [PubMed]
- Mueser, K.T.; Goodman, L.B.; Trumbetta, S.L.; Rosenberg, S.D.; Osher, F.C.; Vidaver, R.; Auciello, P.; Foy, D.W. Traumatic and posttraumatic stress disorder in severe mental illness. J. Consult. Clin. Psychol. 1998, 66, 493–499. [Google Scholar] [CrossRef]
- Zimmerman, M.; Mattia, J.I. Is posttraumatic stress disorder underdiagnosed in routine clinical settings? J. Nerv. Ment. Dis. 1999, 187, 420–428. [Google Scholar] [CrossRef]
- Kostro, K.; Lerman, J.B.; Attia, E. The current status of suicide and self-injury in eating disorders: A narrative review. J. Eat. Disord. 2014, 2, 19. [Google Scholar] [CrossRef]
- Amiri, S.; Khan, M. Prevalence of non-suicidal self-injury, suicidal ideation, suicide attempts, suicide mortality in eating disorders: A systematic review and meta-analysis. Eat. Disord. 2023, 31, 487–525. [Google Scholar] [CrossRef] [PubMed]
- Sander, J.; Moessner, M.; Bauer, S. Depression, Anxiety and Eating Disorder-Related Impairment: Moderators in Female Adolescents and Young Adults. Int. J. Environ. Res. Public Health 2021, 18, 2779. [Google Scholar] [CrossRef] [PubMed]
- Fairburn, C. Evidence-based treatment of anorexia nervosa. Int. J. Eat. Disord. 2005, 37, S26–S30. [Google Scholar] [CrossRef]
- Berkman, N.; Lohr, K.; Bulik, C. Outcomes of Eating Disorders: A Systematic Review of the Literature. Int. J. Eat. Disord. 2007, 40, 293–309. [Google Scholar] [CrossRef] [PubMed]
- Shapiro, J.; Berkman, N.; Brownley, K.; Sedway, J.; Lohr, K.; Bulik, C. Bulimia Nervosa Treatment: A Systematic Review of Randomized Controlled Trials. Int. J. Eat. Disord. 2007, 40, 321–336. [Google Scholar] [CrossRef]
- Bulik, C.; Berkman, N.; Brownley, K.; Sedway, J.; Lohr, K. Anorexia Nervosa Treatment: A Systematic Review of Randomized Controlled Trials. Int. J. Eat. Disord. 2007, 40, 310–320. [Google Scholar] [CrossRef]
- Fichter, M.M.; Quadflieg, N. Twelve-year course and outcome of bulimia nervosa. Psychol. Med. 2004, 34, 1395–1406. [Google Scholar] [CrossRef] [PubMed]
- Mahon, J.; Bradeley, S.N.; Harvey, P.K.; Winston, A.P.; Paler, R.L. Childhood trauma has dose-effect relationship with dropping out from psychotherapeutic treatment for bulimia nervosa: A replication. International. J. Eat. Disord. 2001, 30, 138–148. [Google Scholar] [CrossRef] [PubMed]
- Schmidt, U.H.; Claudino, A.; Fernández-Aranda, F.; Giel, K.E.; Griffiths, J.; Hay, P.J.; Kim, Y.R.; Marshall, J.; Micali, N.; Monteleone, A.M.; et al. The current clinical approach to feeding and eating disorders aimed to increase personalization of management. World Psychiatry 2025, 24, 4–31. [Google Scholar] [CrossRef] [PubMed]
Comorbid Diagnoses | No | % |
---|---|---|
Depression | 34 | 28.8 |
Anxiety disorder | 16 | 13.6 |
Obsessive compulsive disorder | 15 | 12.7 |
Borderline personality disorder | 4 | 3.4 |
Oppositional defiant disorder | 4 | 3.4 |
Substance use disorder | 3 | 2.5 |
Social phobia | 3 | 2.5 |
Total | 86 | 72.8 |
Traumatic Events | n | % |
---|---|---|
Bullying | 27 | 47.3 |
Psychological abuse or neglect | 17 | 29.8 |
Sexual abuse | 16 | 28.1 |
Sickness in the family | 14 | 24.6 |
Physical abuse | 12 | 21.1 |
Family violence witness | 10 | 17.5 |
Accidents or natural catastrophes | 2 | 3.5 |
Own sickness or hospitalisation | 1 | 1.8 |
Variables | PTSD+ (n = 57) Mean (SD) | PTSD− (n = 61) Mean (SD) | U Mann–Whitney | p |
---|---|---|---|---|
Age | 15 (1.5) | 14.8 (1.6) | 1583.0 | 0.391 |
Nº of comorbid diagnoses | 0.8 (0.7) | 0.7 (0.8) | 1607.5 | 0.444 |
Days admitted in EDDCH | 166.1 (78.1) | 176.1 (153.4) | 1441.5 | 0.320 |
Nº of admissions in EDDCH | 1.6 (0.8) | 1.6 (1.2) | 1553 | 0.249 |
Nº of hospitalisation | 1.4 (1.2) | 1.3 (1.3) | 1586 | 0.390 |
Nº of days hospitalised | 51.7 (71.8) | 44.5 (51.9) | 1680.5 | 0.753 |
EAT-40 total | 73.6 (19.1) | 58.7 (23.3) | Students-t test 974.5 | p <0.001 |
CDI | 31.2 (8.4) | 24.1 (7.5) | −4.8 | <0.001 |
PTSD+ (n = 57) | PTSD− (n = 61) | Chi-Square | p | |
---|---|---|---|---|
Suicide attempts | 21 (36%) | 9 (14.7%) | 8.077 | 0.004 |
Non-suicidal self-injury | 39 (67.2%) | 31 (50.8%) | 4.632 | 0.031 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Rodríguez-Rey, A.; Piazza-Suprani, F.; Tasa-Vinyals, E.; Plana, M.T.; Flamarique, I.; Primé-Tous, M.; Moreno, E.; Hilker, I.; Pujal, E.; Martínez, E.; et al. Traumatic Events and Post-Traumatic Stress Disorder in Adolescents with Severe Eating Disorder Admitted to a Day Care Hospital. Nutrients 2025, 17, 2125. https://doi.org/10.3390/nu17132125
Rodríguez-Rey A, Piazza-Suprani F, Tasa-Vinyals E, Plana MT, Flamarique I, Primé-Tous M, Moreno E, Hilker I, Pujal E, Martínez E, et al. Traumatic Events and Post-Traumatic Stress Disorder in Adolescents with Severe Eating Disorder Admitted to a Day Care Hospital. Nutrients. 2025; 17(13):2125. https://doi.org/10.3390/nu17132125
Chicago/Turabian StyleRodríguez-Rey, Arturo, Flavia Piazza-Suprani, Elisabet Tasa-Vinyals, Maria Teresa Plana, Itziar Flamarique, Mireia Primé-Tous, Elena Moreno, Ines Hilker, Ester Pujal, Esteban Martínez, and et al. 2025. "Traumatic Events and Post-Traumatic Stress Disorder in Adolescents with Severe Eating Disorder Admitted to a Day Care Hospital" Nutrients 17, no. 13: 2125. https://doi.org/10.3390/nu17132125
APA StyleRodríguez-Rey, A., Piazza-Suprani, F., Tasa-Vinyals, E., Plana, M. T., Flamarique, I., Primé-Tous, M., Moreno, E., Hilker, I., Pujal, E., Martínez, E., & Andrés-Perpiñá, S. (2025). Traumatic Events and Post-Traumatic Stress Disorder in Adolescents with Severe Eating Disorder Admitted to a Day Care Hospital. Nutrients, 17(13), 2125. https://doi.org/10.3390/nu17132125