Reduction in Remnant Cholesterol in Obese Individuals After Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
Limitations
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Dependent Variables | Before Surgery | After Surgery | Changes | 95% CI | p-Value |
---|---|---|---|---|---|
RC | |||||
All | 0.466 | 0.204 | −0.262 | −0.293; −0.230 | <0.001 |
RYGB | 0.499 | 0.228 | −0.272 | −0.306; −0.237 | <0.001 |
SG | 0.415 | 0.195 | −0.220 | −0.292; −0.147 | <0.001 |
HbA1c | |||||
All | 5.501 | 5.172 | −0.330 | −0.402; −0.258 | <0.001 |
RYGB | 5.460 | 5.115 | −0.344 | −0.424; −0.265 | <0.001 |
SG | 5.517 | 5.253 | −0.264 | −0.432; −0.097 | 0.002 |
Lipids | BMI B-Value (95% CI) p-Value | CRP B-Value (95% CI) p-Value | HbA1c B-Value (95% CI) p-Value |
---|---|---|---|
Triglycerides (mmol/L) | 0.013 (−0.003; 0.029) p = 0.100 | 0.023 (0.007; 0.039) p = 0.005 | 0.180 (0.104; 0.256) p < 0.001 |
Cholesterol (mmol/L) | 0.018 (−0.012; 0.048) p = 0.235 | 0.023 (−0.009; 0.055) p = 0.159 | 0.133 (−0.010; 0.277) p = 0.068 |
HDL-c (mmol/L) | −0.013 (−0.023; −0.003) p = 0.013 | −0.001 (−0.010; 0.009) p = 0.872 | −0.015 (−0.068; 0.038) p = 0.584 |
Non-HDL-c (mmol/L) | 0.030 (0.000; 0.059) p = 0.049 | 0.030 (−0.001; 0.060) p = 0.060 | 0.143 (0.000; 0.287) p = 0.050 |
LDL-c (mmol/L) | 0.026 (−0.002; 0.054) p = 0.070 | 0.017 (−0.012; 0.047) p = 0.243 | 0.100 (−0.035; 0.234;) p = 0.145 |
LDL-c/HDL-c ratio | 0.049 (0.017; 0.081) p = 0.003 | 0.060 (0.029; 0.091) p < 0.001 | 0.127 (−0.033; 0.287) p = 0.119 |
ApoB | 0.006 (−0.001; 0.014) p = 0.103 | 0.006 (−0.001; 0.014) p = 0.101 | 0.035 (−0.001; 0.072) p = 0.058 |
ApoA1 | −0.003 (−0.011; 0.004) p = 0.388 | 0.003 (−0.005; 0.010) p = 0.516 | 0.015 (−0.025; 0.054) p = 0.471 |
ApoB/ApoA1 ratio | 0.009 (0.001; 0.016) p = 0.020 | 0.009 (0.002; 0.017) p = 0.011 | 0.017 (−0.019; 0.053) p = 0.347 |
Remnant cholesterol (mmol/L) | 0.003 (−0.003; 0.009) p = 0.370 | 0.013 (0.006; 0.019) p < 0.001 | 0.046 (0.016; 0.076) p = 0.003 |
Dependent Variable | Cholesterol B-Value (95% CI) p-Value | HDL-c B-Value (95% CI) p-Value | LDL-c B-Value (95% CI) p-Value | Triglycerides B-Value (95% CI) p-Value | ApoB B-Value (95% CI) p-Value | ApoA1 B-Value (95% CI) p-Value | ApoB/ApoA1 Ratio B-Value (95% CI) p-Value |
---|---|---|---|---|---|---|---|
Remnant cholesterol (mmol/L) | 0.057 (0.030; 0.083) <0.001 | −0.232 (−0.306; −0.158) <0.001 | 0.040 (0.010; 0.069) 0.008 | 0.279 (0.243; 0.314) <0.001 | 0.220 (0.110; 0.331) <0.001 | −0.091 (−0.201; 0.020) 0.107 | 0.289 (0.177; 0.401) <0.001 |
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Aaseth, J.O.; Retterstøl, K.; Rootwelt, H.; Farup, P.G. Reduction in Remnant Cholesterol in Obese Individuals After Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy. Nutrients 2025, 17, 189. https://doi.org/10.3390/nu17010189
Aaseth JO, Retterstøl K, Rootwelt H, Farup PG. Reduction in Remnant Cholesterol in Obese Individuals After Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy. Nutrients. 2025; 17(1):189. https://doi.org/10.3390/nu17010189
Chicago/Turabian StyleAaseth, Jan O., Kjetil Retterstøl, Helge Rootwelt, and Per G. Farup. 2025. "Reduction in Remnant Cholesterol in Obese Individuals After Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy" Nutrients 17, no. 1: 189. https://doi.org/10.3390/nu17010189
APA StyleAaseth, J. O., Retterstøl, K., Rootwelt, H., & Farup, P. G. (2025). Reduction in Remnant Cholesterol in Obese Individuals After Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy. Nutrients, 17(1), 189. https://doi.org/10.3390/nu17010189