The Influence of Alcohol Consumption on Intestinal Nutrient Absorption: A Comprehensive Review
Abstract
:1. Introduction
2. Alcohol Use
The Effect of Alcohol Consumption on the Gastrointestinal Tract
3. The Impact of Ethanol on Intestinal Nutrient Absorption
3.1. The Effect of Ethanol on Micronutrient Absorption
3.1.1. Vitamin B1 Absorption
3.1.2. Vitamin B2 Absorption
3.1.3. Vitamin B7 (Biotin) Absorption
3.1.4. Vitamin B9 Absorption
3.1.5. Vitamin C Absorption
3.1.6. Vitamin B12 Absorption
3.2. The Effect of Ethanol on Micronutrients—Minerals
3.2.1. Iron Absorption
3.2.2. Zinc and Selenium Absorption
3.3. The Effect of Ethanol on Macronutrients—Fats
3.4. The Effect of Ethanol on Macronutrients—Carbohydrates
Glucose Absorption
3.5. Peptides and Amino Acids Absorption
Glutamine Absorption
4. Conclusions and Future Perspectives
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Nutrient | Effect on Absorption | Dosage of Ethanol | Location | References |
---|---|---|---|---|
Amino Acids | ↓ | Heavy Binge | SI | [6,105] |
Peptides | ↓, n/c * | Heavy | Duodenum | [78,79] |
Lipids | ↓, n/c * | Heavy | Duodenum SI | [68,75,77,78,79,106] |
Water | ↓ | Heavy | Jejunum | [15,17] |
Nutrient | Effect on Absorption | Dosage | Location | References |
---|---|---|---|---|
Vitamin B1 | ↓ or n/c * | Heavy Binge | Jejunum, HuTu-80 cells | [11,83,84,85,86,87,88,89] |
Vitamin B2 | ↓ | Heavy | Jejunum, Colon | [90] |
Vitamin B7 | ↓ | Heavy | SI, Colon | [107,108] |
Vitamin B9 | ↓, n/c * | Heavy Binge | Jejunum | [8,16,91,92,93,94,109] |
Vitamins A, D, E, B6, B12, and K | ↓ | Heavy | SI | [1,13,110] |
Vitamin C | ↑ | Heavy | SI | [95] |
Glucose | ↓ or n/c **,#,## | Heavy Binge Moderate | SI, Jejunum, IEC-18 cells | [7,10,14,17,65,66,67,68,69,70,71,72,73,74,111,112] |
Fructose | n/c | Heavy | SI | [111] |
Glutamine | ↓ | Moderate | IEC-18 cells, Terminal SI | [33] |
Leucine | ↓ or n/c ** | Heavy | Jejunum | [70,72,80,81,82] |
Glycine | ↓ or n/c ** | Heavy | SI | [6,70] |
Xylose, alanine #, ascorbate # | ↓ | Heavy | SI | [18,111] |
Zinc | ↓ | Heavy | SI | [98] |
Calcium | ↓ | Heavy, Moderate | Duodenum | [9,96] |
Iron | ↑ and n/c ### | Heavy | SI | [100,101] |
Magnesium | ↓ | Heavy | SI | [17] |
Selenium | ↑ | Heavy | Duodenum | [104] |
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Butts, M.; Sundaram, V.L.; Murughiyan, U.; Borthakur, A.; Singh, S. The Influence of Alcohol Consumption on Intestinal Nutrient Absorption: A Comprehensive Review. Nutrients 2023, 15, 1571. https://doi.org/10.3390/nu15071571
Butts M, Sundaram VL, Murughiyan U, Borthakur A, Singh S. The Influence of Alcohol Consumption on Intestinal Nutrient Absorption: A Comprehensive Review. Nutrients. 2023; 15(7):1571. https://doi.org/10.3390/nu15071571
Chicago/Turabian StyleButts, Molly, Vijaya Lakshmi Sundaram, Usha Murughiyan, Alip Borthakur, and Soudamani Singh. 2023. "The Influence of Alcohol Consumption on Intestinal Nutrient Absorption: A Comprehensive Review" Nutrients 15, no. 7: 1571. https://doi.org/10.3390/nu15071571