Mapping Research Trends and Hotspots in the Link between Alzheimer’s Disease and Gut Microbes over the Past Decade: A Bibliometric Analysis
Abstract
:1. Introduction
2. Methods
2.1. Data Source and Search Strategy
2.2. Data Analysis
3. Results
3.1. Distribution of Annual Publications and Citations
3.2. Geographical Distribution
3.3. Journals
3.4. Authors and Institutions
3.5. Most Cited Articles
3.6. Keywords
3.6.1. Keywords Co-Occurrence Networks
3.6.2. Keywords with the Strongest Citation Bursts
4. Discussion
Supplementary Materials
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Year | NP | Percent (%) | TC/Y | TC |
---|---|---|---|---|
2012 | 2 | 0.2 | 3.5 | 76 |
2013 | 7 | 0.6 | 6.9 | 486 |
2014 | 6 | 0.5 | 6.8 | 368 |
2015 | 14 | 1.2 | 8.9 | 1001 |
2016 | 25 | 2.1 | 15.1 | 2637 |
2017 | 55 | 4.7 | 20.5 | 6772 |
2018 | 102 | 8.7 | 11.5 | 5840 |
2019 | 134 | 11.5 | 14.5 | 7761 |
2020 | 173 | 14.8 | 8.5 | 4422 |
2021 | 259 | 22.1 | 4.8 | 2476 |
2022 | 393 | 33.6 | 1.4 | 531 |
SCR | Country | NP | Percent (%) | TC | SCP | MCP | MCP_Ratio |
---|---|---|---|---|---|---|---|
1 | China | 374 | 40.7 | 8268 | 316 | 58 | 0.155 |
2 | USA | 208 | 22.6 | 9544 | 146 | 62 | 0.298 |
3 | Italy | 90 | 9.8 | 5159 | 65 | 25 | 0.278 |
4 | Korea | 50 | 5.4 | 1206 | 46 | 4 | 0.08 |
5 | Spain | 40 | 4.4 | 1301 | 29 | 11 | 0.275 |
6 | Australia | 34 | 3.7 | 1070 | 22 | 12 | 0.353 |
7 | Japan | 33 | 3.6 | 674 | 26 | 7 | 0.212 |
8 | Canada | 31 | 3.4 | 1632 | 18 | 13 | 0.419 |
9 | Poland | 31 | 3.4 | 1019 | 28 | 3 | 0.097 |
10 | India | 28 | 3.1 | 462 | 20 | 8 | 0.286 |
Sources | NP | Percent (%) | IF (2021) | Category (JCR) |
---|---|---|---|---|
Journal of Alzheimers Disease | 57 | 4.9 | 4.16 | Neurosciences (Q2) |
Nutrients | 50 | 4.3 | 6.706 | Nutrition and Dietetics (Q1) |
International Journal of Molecular Science | 49 | 4.2 | 6.208 | Biochemistry and Molecular Biology (Q2); Chemistry, Multidisciplinary (Q2) |
Frontiers in Aging Neuroscience | 46 | 3.9 | 5.702 | Neurosciences (Q2); Geriatrics and Gerontology (Q2) |
Frontiers in Neuroscience | 31 | 2.7 | 5.152 | Neurosciences (Q2) |
Scientific Reports | 26 | 2.2 | 4.997 | Multidisciplinary Sciences (Q1) |
Frontiers in Immunology | 21 | 1.8 | 8.787 | Immunology (Q1) |
Frontiers in Pharmacology | 16 | 1.4 | 5.988 | Phamacology and Phamacy (Q1) |
Cells | 13 | 1.1 | 7.666 | Cell Biology (Q2) |
Brain Behavior and Immunity | 12 | 1.0 | 19.227 | Neurosciences (Q1); Immunology (Q1); Psychiatry (Q1) |
SCR | Author (N = 4683) | H-Index | TC | NP | Institution (N = 1940) | NP | Percent (%) |
---|---|---|---|---|---|---|---|
1 | Wang Y | 13 | 770 | 31 | Shanghai Jiaotong University | 66 | 5.6 |
2 | Zhang X | 13 | 1504 | 28 | University of Kentucky | 60 | 5.1 |
3 | ZhangY | 7 | 189 | 26 | Zhejiang University | 59 | 5.0 |
4 | Li Y | 11 | 354 | 25 | Louisiana University | 49 | 4.2 |
5 | Wang X | 10 | 790 | 25 | Fudan University | 41 | 3.5 |
6 | Liu Y | 8 | 184 | 22 | Soochow University | 41 | 3.5 |
7 | Chen Y | 10 | 487 | 17 | Capital Medical University | 39 | 3.3 |
8 | Liu J | 8 | 788 | 17 | Peking University | 38 | 3.3 |
9 | Zhang L | 7 | 566 | 17 | University College Cork | 37 | 3.2 |
10 | Zhao Y | 7 | 419 | 17 | Central South University | 36 | 3.1 |
SCR | Author and Year | Title | Journal (IF-2022) | TC | TC/Y |
---|---|---|---|---|---|
1 | Cryan JF, 2019 [19] | The Microbiota-Gut-Brain Axis | Physiological Reviews (46.513; Q1) | 1212 | 242.4 |
2 | Rinninella E, 2019 [20] | What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases | Microorganisms (4.926; Q3) | 980 | 196.0 |
3 | Fung TC, 2017 [21] | Interactions between the microbiota, immune and nervous systems in health and disease | Nature Neuroscience (28.771; Q1) | 887 | 126.7 |
4 | Vogt NM, 2017 [10] | Gut microbiome alterations in Alzheimer’s disease | Scientific Reports (4.997; Q3) | 809 | 115.6 |
5 | Hickman S, 2018 [22] | Microglia in neurodegeneration | Nature Neuroscience (28.771; Q1) | 635 | 105.8 |
6 | Cattaneo A, 2017 [23] | Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly | Neurobiology of Aging (5.133; Q2/3) | 578 | 82.6 |
7 | Wang X, 2019 [24] | Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression | Cell Research (46.351, Q1) | 445 | 89.0 |
8 | Akbari E, 2016 [25] | Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer’s Disease: A Randomized, Double-Blind and Controlled Trial | Frontiers in Aging Neuroscience (5.702; Q2/3) | 423 | 52.9 |
9 | Harach T, 2017 [26] | Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota | Scientific Reports (4.997; Q3) | 418 | 59.7 |
10 | Jiang C, 2017 [27] | The Gut Microbiota and Alzheimer’s Disease | Journal of Alzheimers Disease (4.160, Q3) | 394 | 56.3 |
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Xiu, R.; Sun, Q.; Li, B.; Wang, Y. Mapping Research Trends and Hotspots in the Link between Alzheimer’s Disease and Gut Microbes over the Past Decade: A Bibliometric Analysis. Nutrients 2023, 15, 3203. https://doi.org/10.3390/nu15143203
Xiu R, Sun Q, Li B, Wang Y. Mapping Research Trends and Hotspots in the Link between Alzheimer’s Disease and Gut Microbes over the Past Decade: A Bibliometric Analysis. Nutrients. 2023; 15(14):3203. https://doi.org/10.3390/nu15143203
Chicago/Turabian StyleXiu, Ruipu, Qingyuan Sun, Boya Li, and Yanqing Wang. 2023. "Mapping Research Trends and Hotspots in the Link between Alzheimer’s Disease and Gut Microbes over the Past Decade: A Bibliometric Analysis" Nutrients 15, no. 14: 3203. https://doi.org/10.3390/nu15143203
APA StyleXiu, R., Sun, Q., Li, B., & Wang, Y. (2023). Mapping Research Trends and Hotspots in the Link between Alzheimer’s Disease and Gut Microbes over the Past Decade: A Bibliometric Analysis. Nutrients, 15(14), 3203. https://doi.org/10.3390/nu15143203