Severity of Inflammation Is Associated with Food Intake in Hospitalized Geriatric Patients—A Merged Data Analysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Assessment of Nutritional Status and Food Intake
2.2. Geriatric Assessment
2.3. Assessment of C-Reactive Protein
2.4. Data Analysis
3. Results
3.1. Baseline Characteristics
3.2. Comparison of CRP Concentrations across the MNA-SF and Food Intake Levels
3.3. Relationship between Inflammation and Food Intake
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Total Population (n = 1650) | |
---|---|
Gender | |
Female (n; %) | 1047 (63) |
Male (n; %) | 603 (37) |
Age (y) | 79.6 ± 7.4 |
Height (m) | 1.60 ± 0.10 |
Actual body weight (kg) | 70.8 ± 17.6 |
BMI (kg/m2) | 27.3 ± 6.1 |
MNA-SF, Median (IQR) | 10 (7–12) |
Malnourished (n; %) | 457 (28) |
At risk of malnutrition (n; %) | 675 (41) |
Normal nutritional status (n; %) | 518 (31) |
MNA-SF, reduction in food intake | |
Severe decrease in food intake (n; %) | 200 (12) |
Moderate decrease in food intake (n; %) | 578 (35) |
No decrease in food intake (n; %) | 872 (53) |
CRP (mg/dL) | 2.6 ± 5.3 |
No inflammation (0.0–0.49 (mg/dL), n; %) | 881 (53) |
Mild inflammation (0.5–3.0 (mg/dL), n; %) | 393 (24) |
Moderate to severe inflammation (≥3.0 (mg/dL), n; %) | 376 (23) |
Severe Decrease in Food Intake | |||||
---|---|---|---|---|---|
B | Std. Error | Beta | t | p Value | |
CRP levels (<3 and ≥3 mg/dL) | −0.172 | 0.021 | −0.229 | −8.217 | <0.000 |
Age | −0.001 | 0.001 | −0.031 | −1.123 | 0.262 |
Gender | −0.045 | 0.017 | −0.073 | −2.693 | 0.007 |
CCI | 0.006 | 0.004 | 0.041 | 1.506 | 0.511 |
Moderate and severe decrease in food intake | |||||
CRP levels (<3 and ≥3 mg/dL) | −0.359 | 0.034 | −0.287 | −10.674 | <0.000 |
Age | −0.005 | 0.002 | −0.072 | −2.709 | 0.007 |
Gender | −0.198 | 0.027 | −0.194 | −7.452 | <0.000 |
CCI | 0.013 | 0.007 | −0.051 | −1.954 | 0.053 |
Malnutrition | |||||
CRP levels (<3 and ≥3 mg/dL) | −0.222 | 0.029 | −0.212 | −7.730 | <0.000 |
Age | −0.009 | 0.002 | −0.164 | −4.993 | <0.000 |
Gender | −0.055 | 0.023 | −0.065 | −2.442 | 0.015 |
CCI | −0.015 | 0.006 | −0.067 | −2.507 | 0.012 |
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Pourhassan, M.; Cederholm, T.; Donini, L.M.; Poggiogalle, E.; Schwab, U.; Nielsen, R.L.; Andersen, A.L.; Małgorzewicz, S.; Volkert, D.; Wirth, R. Severity of Inflammation Is Associated with Food Intake in Hospitalized Geriatric Patients—A Merged Data Analysis. Nutrients 2023, 15, 3079. https://doi.org/10.3390/nu15143079
Pourhassan M, Cederholm T, Donini LM, Poggiogalle E, Schwab U, Nielsen RL, Andersen AL, Małgorzewicz S, Volkert D, Wirth R. Severity of Inflammation Is Associated with Food Intake in Hospitalized Geriatric Patients—A Merged Data Analysis. Nutrients. 2023; 15(14):3079. https://doi.org/10.3390/nu15143079
Chicago/Turabian StylePourhassan, Maryam, Tommy Cederholm, Lorenzo M. Donini, Eleonora Poggiogalle, Ursula Schwab, Rikke Lundsgaard Nielsen, Aino Leegaard Andersen, Sylwia Małgorzewicz, Dorothee Volkert, and Rainer Wirth. 2023. "Severity of Inflammation Is Associated with Food Intake in Hospitalized Geriatric Patients—A Merged Data Analysis" Nutrients 15, no. 14: 3079. https://doi.org/10.3390/nu15143079
APA StylePourhassan, M., Cederholm, T., Donini, L. M., Poggiogalle, E., Schwab, U., Nielsen, R. L., Andersen, A. L., Małgorzewicz, S., Volkert, D., & Wirth, R. (2023). Severity of Inflammation Is Associated with Food Intake in Hospitalized Geriatric Patients—A Merged Data Analysis. Nutrients, 15(14), 3079. https://doi.org/10.3390/nu15143079