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Article
Peer-Review Record

Second-Trimester Constituents of the Metabolic Syndrome and Pregnancy Outcome: An Observational Cohort Study

Nutrients 2022, 14(14), 2933; https://doi.org/10.3390/nu14142933
by Jonas Ellerbrock 1,2,*, Esmee Hubers 3, Chahinda Ghossein-Doha 1,4, Veronique Schiffer 1,2, Robert-Jan Alers 1,5, Laura Jorissen 1,5, Jolijn van Neer 5, Maartje Zelis 2, Emma Janssen 1,5, Sabine Landewé-Cleuren 6, Annemie van Haarlem 6, Boris Kramer 7 and Marc Spaanderman 1,3,5
Reviewer 1: Anonymous
Reviewer 2:
Nutrients 2022, 14(14), 2933; https://doi.org/10.3390/nu14142933
Submission received: 14 June 2022 / Revised: 11 July 2022 / Accepted: 13 July 2022 / Published: 18 July 2022
(This article belongs to the Special Issue The Interplay between Maternal Nutrition and Oxidative Stress)

Round 1

Reviewer 1 Report

The paper has the merrit to investigate the metabolic syndrome related to GD. Thde conclusion of the authors is that if the diabetes is well control the perinatal outcome is good. The paper respects the scientific rigour. 

I think the article bring the evidence that an early diagnosis is the key of implemting a correct therapy to prevent complications.

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

 

Major revision

The manuscript: “Second Trimester Constituents of the Metabolic Syndrome and Pregnancy Outcome; an observational cohort study” studied the relationship between metabolic syndrome and impaired gestational glucose tolerance on subsequent maternal and neonatal outcome. (preeclampsia, altered fetal growth and preterm birth).

The manuscript is well written. The conclusion are in concordance with the results.

Why the obesity are not in relation with neonatal outcome?

 

Minor revision

Please delete the point after the title.

On page 1 line 26 what is OGTT? Please explain the acronym.

On page 1 line 30: ….. the risk of SGA (aOR 1.59), PE (aOR 3.14), preterm birth <37 weeks (aOR 2.17) and <34 weeks 30 (aOR 2.96). Please delete “a” from parentheses.

In tables acronyms are not explained.

Author Response

Please see the attachment.

Author Response File: Author Response.docx

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