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Comment published on 10 November 2021, see Nutrients 2021, 13(11), 4005.
Review

The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease

1
Students’ Scientific Circle of Clinical Nutrition, Medical University of Gdansk, 80-211 Gdańsk, Poland
2
Department of Clinical Nutrition and Dietetics, Medical University of Gdansk, 80-211 Gdańsk, Poland
3
Department of Surgical Oncology, Medical University of Gdansk, 80-210 Gdansk, Poland
4
Department of Biochemical Sciences, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland
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Department of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, 80-210 Gdańsk, Poland
6
Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: William B. Grant
Nutrients 2021, 13(7), 2125; https://doi.org/10.3390/nu13072125
Received: 30 May 2021 / Revised: 17 June 2021 / Accepted: 18 June 2021 / Published: 22 June 2021
(This article belongs to the Special Issue Diet, Inflammation, and Infectious Diseases)
Gastrointestinal symptoms in Crohn’s disease (CD) are common and affect the quality of life of patients; consequently, a growing number of studies have been published on diet interventions in this group. The role of the gut microbiota in the pathogenesis and the progression of inflammatory bowel diseases (IBD), including CD, has been widely discussed. Mainly, a decreased abundance of Firmicutes, species of the Bifidobacterium genus, and the Faecalibacterium prausnitzii species as well as a reduced general diversity have been described. In this review article, we summarize available data on the influence of reduction diets on the microbiome of patients with CD. One of the most frequently used elimination diets in CD patients is the low-FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols) diet. Although many papers show it may reduce abdominal pain, diarrhea, or bloating, it also reduces the intake of prebiotic substances, which can negatively affect the gut microbiota composition, decreasing the abundance of Bifidobacterium species and Faecalibacterium prausnitzii. Other elimination diets used by IBD patients, such as lactose-free or gluten-free diets, have also been shown to disturb the microbial diversity. On the other hand, CDED (Crohn’s disease exclusion diet) with partial enteral nutrition not only induces the remission of CD but also has a positive influence on the microbiota. The impact of diet interventions on the microbiota and, potentially, on the future course of the disease should be considered when nutritional guidelines for IBD patients are designed. Dietetic recommendations should be based not only on the regulation of the symptoms but also on the long-term development of the disease. View Full-Text
Keywords: Crohn’s disease; elimination diets; microbiome Crohn’s disease; elimination diets; microbiome
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MDPI and ACS Style

Starz, E.; Wzorek, K.; Folwarski, M.; Kaźmierczak-Siedlecka, K.; Stachowska, L.; Przewłócka, K.; Stachowska, E.; Skonieczna-Żydecka, K. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. Nutrients 2021, 13, 2125. https://doi.org/10.3390/nu13072125

AMA Style

Starz E, Wzorek K, Folwarski M, Kaźmierczak-Siedlecka K, Stachowska L, Przewłócka K, Stachowska E, Skonieczna-Żydecka K. The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease. Nutrients. 2021; 13(7):2125. https://doi.org/10.3390/nu13072125

Chicago/Turabian Style

Starz, Eliza, Karolina Wzorek, Marcin Folwarski, Karolina Kaźmierczak-Siedlecka, Laura Stachowska, Katarzyna Przewłócka, Ewa Stachowska, and Karolina Skonieczna-Żydecka. 2021. "The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease" Nutrients 13, no. 7: 2125. https://doi.org/10.3390/nu13072125

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