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Review

Effect of Microalgae and Macroalgae Extracts on Non-Alcoholic Fatty Liver Disease

1
Nutrition and Obesity Group, Department of Pharmacy and Food Science, Faculty of Pharmacy and Lucio Lascaray Research Center, University of the Basque Country (UPV/EHU), 01008 Vitoria-Gasteiz, Spain
2
Bioaraba Health Research Institute, 01006 Vitoria-Gasteiz, Spain
3
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III (ISCIII), 28222 Madrid, Spain
*
Authors to whom correspondence should be addressed.
Academic Editors: Iain A. Brownlee and Matthew D. Wilcox
Nutrients 2021, 13(6), 2017; https://doi.org/10.3390/nu13062017
Received: 17 May 2021 / Revised: 8 June 2021 / Accepted: 9 June 2021 / Published: 11 June 2021
(This article belongs to the Special Issue Potential Health Benefits of Dietary Algae)
The present review aims to gather scientific evidence regarding the beneficial effects of microalgae and macroalgae extracts on non-alcoholic fatty liver disease (NAFLD). The described data show that both microalgae and macroalgae improved this alteration. The majority of the reported studies analysed the preventive effects because algae were administered to animals concurrent with the diet that induced NAFLD. The positive effects were demonstrated using a wide range of doses, from 7.5 to 300 mg/kg body weight/day or from 1 to 10% in the diet, and experimental periods ranged from 3 to 16 weeks. Two important limitations on the scientific knowledge available to date are that very few studies have researched the mechanisms of action underlying the preventive effects of microalgae on NAFLD and that, for the majority of the algae studied, a single paper has been reported. For these reasons, it is not possible to establish the best conditions in order to know the beneficial effects that these algae could bring. In this scenario, further studies are needed. Moreover, the beneficial effects of algae observed in rodent need to be confirmed in humans before we can start considering these products as new tools in the fight against fatty liver disease. View Full-Text
Keywords: non-alcoholic fatty liver disease; liver steatosis; macroalgae; microalgae non-alcoholic fatty liver disease; liver steatosis; macroalgae; microalgae
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MDPI and ACS Style

González-Arceo, M.; Gómez-Zorita, S.; Aguirre, L.; Portillo, M.P. Effect of Microalgae and Macroalgae Extracts on Non-Alcoholic Fatty Liver Disease. Nutrients 2021, 13, 2017. https://doi.org/10.3390/nu13062017

AMA Style

González-Arceo M, Gómez-Zorita S, Aguirre L, Portillo MP. Effect of Microalgae and Macroalgae Extracts on Non-Alcoholic Fatty Liver Disease. Nutrients. 2021; 13(6):2017. https://doi.org/10.3390/nu13062017

Chicago/Turabian Style

González-Arceo, Maitane, Saioa Gómez-Zorita, Leixuri Aguirre, and María P. Portillo 2021. "Effect of Microalgae and Macroalgae Extracts on Non-Alcoholic Fatty Liver Disease" Nutrients 13, no. 6: 2017. https://doi.org/10.3390/nu13062017

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