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Review

Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products

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Department of Pharmaceutical Chemistry, Drug Analyses and Radiopharmacy, Faculty of Pharmacy, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland
2
Department of Radiobiology and Radiation Protection, Military Institute of Hygiene and Epidemiology, 4 Kozielska St., 01-163 Warsaw, Poland
*
Authors to whom correspondence should be addressed.
Academic Editors: Kimber L. Stanhope and Rosa Casas
Nutrients 2021, 13(6), 1957; https://doi.org/10.3390/nu13061957
Received: 12 May 2021 / Revised: 27 May 2021 / Accepted: 3 June 2021 / Published: 7 June 2021
(This article belongs to the Section Nutrition and Public Health)
Aspartame is a sweetener introduced to replace the commonly used sucrose. It was discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its intake was expected to reduce obesity rates in developing countries and help those struggling with diabetes. It is mainly used as a sweetener for soft drinks, confectionery, and medicines. Despite its widespread use, its safety remains controversial. This narrative review investigates the existing literature on the use of aspartame and its possible effects on the human body to refine current knowledge. Taking to account that aspartame is a widely used artificial sweetener, it seems appropriate to continue research on safety. Studies mentioned in this article have produced very interesting results overall, the current review highlights the social problem of providing visible and detailed information about the presence of aspartame in products. The studies involving the impact of aspartame on obesity, diabetes mellitus, children and fetus, autism, neurodegeneration, phenylketonuria, allergies and skin problems, its cancer properties and its genotoxicity were analyzed. Further research should be conducted to ensure clear information about the impact of aspartame on health. View Full-Text
Keywords: aspartame; artificial sweeteners; cancer; metabolism; neurodegeneration aspartame; artificial sweeteners; cancer; metabolism; neurodegeneration
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MDPI and ACS Style

Czarnecka, K.; Pilarz, A.; Rogut, A.; Maj, P.; Szymańska, J.; Olejnik, Ł.; Szymański, P. Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products. Nutrients 2021, 13, 1957. https://doi.org/10.3390/nu13061957

AMA Style

Czarnecka K, Pilarz A, Rogut A, Maj P, Szymańska J, Olejnik Ł, Szymański P. Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products. Nutrients. 2021; 13(6):1957. https://doi.org/10.3390/nu13061957

Chicago/Turabian Style

Czarnecka, Kamila, Aleksandra Pilarz, Aleksandra Rogut, Patryk Maj, Joanna Szymańska, Łukasz Olejnik, and Paweł Szymański. 2021. "Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products" Nutrients 13, no. 6: 1957. https://doi.org/10.3390/nu13061957

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