Next Article in Journal
Short-Chain Fatty Acids, Maternal Microbiota and Metabolism in Pregnancy
Next Article in Special Issue
Selenium as a Bioactive Micronutrient in the Human Diet and Its Cancer Chemopreventive Activity
Previous Article in Journal
Maternal Dietary Selenium Intake during Pregnancy and Neonatal Outcomes in the Norwegian Mother, Father, and Child Cohort Study
Article

Coffee Consumption and All-Cause, Cardiovascular, and Cancer Mortality in an Adult Mediterranean Population

1
Instituto de Investigación Sanitaria y Biomédica de Alicante, ISABIAL-UMH, 03010 Alicante, Spain
2
Unidad de Epidemiología de la Nutrición, Departamento de Salud Pública, Historia de la Ciencia y Ginecología, Universidad Miguel Hernández (UMH), 03550 Alicante, Spain
3
CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, 28034 Madrid, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Stefano Realdon
Nutrients 2021, 13(4), 1241; https://doi.org/10.3390/nu13041241
Received: 17 March 2021 / Revised: 4 April 2021 / Accepted: 7 April 2021 / Published: 9 April 2021
(This article belongs to the Special Issue Human Nutrition and Cancer Prevention)
We assessed the association between usual coffee consumption and all-cause, cardiovascular (CV), and cancer mortality in an adult population in Spain, taking into account both the amount and type of coffee consumed. We used baseline data on coffee consumption and other personal variables, and the number of deaths during an 18-year follow-up period, for 1567 participants aged 20 years and older from the Valencia Nutrition Study in Spain. Total, caffeinated, and decaffeinated coffee consumption was assessed using a validated food frequency questionnaire. Cox regression models were used to estimate adjusted hazard ratios (HRs) and 95% confidence intervals (CIs). During the 18-year follow-up period, 317 died; 115 due to CV disease and 82 due to cancer. Compared with no-consumption, the consumption of ≤1 cup per day and >1 cup per day of coffee was associated with a lower risk of all-cause mortality, HR = 0.73 (95% CI: 0.56–0.97) and HR 0.56 (95% CI: 0.41–0.77), respectively. A lower cancer mortality was observed among drinkers of more than 1 cup per day compared with nondrinkers, HR 0.41 (95% CI 0.20–0.86). Regarding the type of coffee, only the overall consumption of caffeinated coffee was associated with lower all-cause mortality at 12 and 18 years of follow-up, HR = 0.66 (95% CI:0.46–0.94) and HR = 0.59 (95% CI: 0.44–0.79), respectively. In conclusion, this study suggests that the moderate consumption of coffee, particularly caffeinated coffee (range 1–6.5 cups per day), is associated with a lower all-cause and cancer mortality after a long follow-up period. No significant association was found between coffee consumption and CVD mortality. View Full-Text
Keywords: coffee; caffeinated; decaffeinated; mortality; cardiovascular disease; cancer coffee; caffeinated; decaffeinated; mortality; cardiovascular disease; cancer
Show Figures

Graphical abstract

MDPI and ACS Style

Torres-Collado, L.; Compañ-Gabucio, L.M.; González-Palacios, S.; Notario-Barandiaran, L.; Oncina-Cánovas, A.; Vioque, J.; García-de la Hera, M. Coffee Consumption and All-Cause, Cardiovascular, and Cancer Mortality in an Adult Mediterranean Population. Nutrients 2021, 13, 1241. https://doi.org/10.3390/nu13041241

AMA Style

Torres-Collado L, Compañ-Gabucio LM, González-Palacios S, Notario-Barandiaran L, Oncina-Cánovas A, Vioque J, García-de la Hera M. Coffee Consumption and All-Cause, Cardiovascular, and Cancer Mortality in an Adult Mediterranean Population. Nutrients. 2021; 13(4):1241. https://doi.org/10.3390/nu13041241

Chicago/Turabian Style

Torres-Collado, Laura, Laura M. Compañ-Gabucio, Sandra González-Palacios, Leyre Notario-Barandiaran, Alejandro Oncina-Cánovas, Jesús Vioque, and Manuela García-de la Hera. 2021. "Coffee Consumption and All-Cause, Cardiovascular, and Cancer Mortality in an Adult Mediterranean Population" Nutrients 13, no. 4: 1241. https://doi.org/10.3390/nu13041241

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop