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The Role of Oat Nutrients in the Immune System: A Narrative Review

Biofortis Research, Mérieux NutriSciences, Addison, IL 60101, USA
Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
Quaker Oats Center of Excellence, PepsiCo Health & Nutrition Sciences, Barrington, IL 60010, USA
PepsiCo Health & Nutrition Sciences, AMESA, Gurgaon 122101, India
Madras Diabetes Research Foundation, Chennai, Tamil Nadu 600086, India
Author to whom correspondence should be addressed.
Academic Editor: Margarida Castell Escuer
Nutrients 2021, 13(4), 1048;
Received: 9 February 2021 / Revised: 18 March 2021 / Accepted: 19 March 2021 / Published: 24 March 2021
(This article belongs to the Section Phytochemicals and Human Health)
Optimal nutrition is the foundation for the development and maintenance of a healthy immune system. An optimal supply of nutrients is required for biosynthesis of immune factors and immune cell proliferation. Nutrient deficiency/inadequacy and hidden hunger, which manifests as depleted nutrients reserves, increase the risk of infectious diseases and aggravate disease severity. Therefore, an adequate and balanced diet containing an abundant diversity of foods, nutrients, and non-nutrient chemicals is paramount for an optimal immune defense against infectious diseases, including cold/flu and non-communicable diseases. Some nutrients and foods play a larger role than others in the support of the immune system. Oats are a nutritious whole grain and contain several immunomodulating nutrients. In this narrative review, we discuss the contribution of oat nutrients, including dietary fiber (β-glucans), copper, iron, selenium, and zinc, polyphenolics (ferulic acid and avenanthramides), and proteins (glutamine) in optimizing the innate and adaptive immune system’s response to infections directly by modulating the innate and adaptive immunity and indirectly by eliciting changes in the gut microbiota and related metabolites. View Full-Text
Keywords: fiber; polyphenols; minerals; protein; human fiber; polyphenols; minerals; protein; human
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MDPI and ACS Style

Chen, O.; Mah, E.; Dioum, E.; Marwaha, A.; Shanmugam, S.; Malleshi, N.; Sudha, V.; Gayathri, R.; Unnikrishnan, R.; Anjana, R.M.; Krishnaswamy, K.; Mohan, V.; Chu, Y. The Role of Oat Nutrients in the Immune System: A Narrative Review. Nutrients 2021, 13, 1048.

AMA Style

Chen O, Mah E, Dioum E, Marwaha A, Shanmugam S, Malleshi N, Sudha V, Gayathri R, Unnikrishnan R, Anjana RM, Krishnaswamy K, Mohan V, Chu Y. The Role of Oat Nutrients in the Immune System: A Narrative Review. Nutrients. 2021; 13(4):1048.

Chicago/Turabian Style

Chen, Oliver, Eunice Mah, ElHadji Dioum, Ankita Marwaha, Shobana Shanmugam, Nagappa Malleshi, Vasudevan Sudha, Rajagopal Gayathri, Ranjit Unnikrishnan, Ranjit M. Anjana, Kamala Krishnaswamy, Viswanathan Mohan, and YiFang Chu. 2021. "The Role of Oat Nutrients in the Immune System: A Narrative Review" Nutrients 13, no. 4: 1048.

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