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Open AccessArticle

Long-Term Effects of Vitamin D Supplementation in Obese Children During Integrated Weight–Loss Programme—A Double Blind Randomized Placebo–Controlled Trial

1
Department of Paediatrics, Gastroenterology, Allergology and Paediatric Nutrition, Medical University of Gdańsk, 80–803 Gdańsk, Poland
2
Department of Public Health and Social Medicine, Medical University of Gdansk, 80–210 Gdańsk, Poland
3
Department of Paediatrics, Copernicus Medical Center, 80-462 Gdańsk, Poland
4
“6–10–14 for Health”–University Clinical Center, 80-952 Gdańsk, Poland
5
Department of Endocrinology and Internal Medicine, Medical University of Gdansk, 80–952 Gdańsk, Poland
6
Department of Gastroenterology, Hepatology and Feeding Disorders, The Children’s Memorial Health Institute, 04–730 Warszawa, Poland
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(4), 1093; https://doi.org/10.3390/nu12041093
Received: 24 March 2020 / Revised: 10 April 2020 / Accepted: 13 April 2020 / Published: 15 April 2020
(This article belongs to the Special Issue Vitamin D in 2020: Stop or Not Yet?)
Background: Vitamin D was studied in regards to its possible impact on body mass reduction and metabolic changes in adults and children with obesity yet there were no studies assessing the impact of vitamin D supplementation during a weight management program in children and adolescence. The aim of our study was to assess the influence of 26 weeks of vitamin D supplementation in overweight and obese children undergoing an integrated 12–months’ long weight loss program on body mass reduction, body composition and bone mineral density. Methods: A double–blind randomized placebo–controlled trial. Vitamin D deficient patients (<30 ng/ml level of vitamin D) aged 6–14, participating in multidisciplinary weight management program were randomly allocated to receiving vitamin D (1200 IU) or placebo for the first 26 weeks of the intervention. Results: Out of the 152 qualified patients, 109 (72%) completed a full cycle of four visits scheduled in the program. There were no difference in the level of BMI (body mass index) change – both raw BMI and BMI centiles. Although the reduction of BMI centiles was greater in the vitamin D vs. placebo group (−4.28 ± 8.43 vs. −2.53 ± 6.10) the difference was not statistically significant (p = 0.319). Similarly the reduction in fat mass—assessed both using bioimpedance and DEXa was achieved, yet the differences between the groups were not statistically significant. Conclusions: Our study ads substantial results to support the thesis on no effect of vitamin D supplementation on body weight reduction in children and adolescents with vitamin D insufficiency undergoing a weight management program. View Full-Text
Keywords: vitamin D; obesity; weight–loss; body composition vitamin D; obesity; weight–loss; body composition
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MDPI and ACS Style

Brzeziński, M.; Jankowska, A.; Słomińska-Frączek, M.; Metelska, P.; Wiśniewski, P.; Socha, P.; Szlagatys-Sidorkiewicz, A. Long-Term Effects of Vitamin D Supplementation in Obese Children During Integrated Weight–Loss Programme—A Double Blind Randomized Placebo–Controlled Trial. Nutrients 2020, 12, 1093.

AMA Style

Brzeziński M, Jankowska A, Słomińska-Frączek M, Metelska P, Wiśniewski P, Socha P, Szlagatys-Sidorkiewicz A. Long-Term Effects of Vitamin D Supplementation in Obese Children During Integrated Weight–Loss Programme—A Double Blind Randomized Placebo–Controlled Trial. Nutrients. 2020; 12(4):1093.

Chicago/Turabian Style

Brzeziński, Michał; Jankowska, Agnieszka; Słomińska-Frączek, Magdalena; Metelska, Paulina; Wiśniewski, Piotr; Socha, Piotr; Szlagatys-Sidorkiewicz, Agnieszka. 2020. "Long-Term Effects of Vitamin D Supplementation in Obese Children During Integrated Weight–Loss Programme—A Double Blind Randomized Placebo–Controlled Trial" Nutrients 12, no. 4: 1093.

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