Evaluation of Non-Celiac Gluten Sensitivity in Patients with Previous Diagnosis of Irritable Bowel Syndrome: A Randomized Double-Blind Placebo-Controlled Crossover Trial
Abstract
:1. Introduction
2. Materials and Methods
3. Study Design
4. Gluten Challenge Phase
5. Nutritional Evaluations and Adherence to the Diet
6. Preparation of Low FODMAP-GFD
7. Statistical Analysis
8. Results
9. Discussion
Author Contributions
Funding
Conflicts of Interest
Abbreviations
References
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Variables | Values at T0 |
---|---|
N. of subjects | 40 (100%) |
male/female° | 10/30 |
age (years) | 40.5 ± 12.5 |
BMI | 24.7 ± 4.1 |
Abdominal pain (%) | 100 |
Abdominal distention (%) | 50 |
Constipation/diarrhea (%) | 38 |
Fatigue (%) | 29 |
Hemoglobin (g/dL) | 14.5 ± 0.8 |
Ferritin (ng/mL) | 183.1 ± 43.6 |
AST (U/mL) | 23.6 ± 3.9 |
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Barone, M.; Gemello, E.; Viggiani, M.T.; Cristofori, F.; Renna, C.; Iannone, A.; Di Leo, A.; Francavilla, R. Evaluation of Non-Celiac Gluten Sensitivity in Patients with Previous Diagnosis of Irritable Bowel Syndrome: A Randomized Double-Blind Placebo-Controlled Crossover Trial. Nutrients 2020, 12, 705. https://doi.org/10.3390/nu12030705
Barone M, Gemello E, Viggiani MT, Cristofori F, Renna C, Iannone A, Di Leo A, Francavilla R. Evaluation of Non-Celiac Gluten Sensitivity in Patients with Previous Diagnosis of Irritable Bowel Syndrome: A Randomized Double-Blind Placebo-Controlled Crossover Trial. Nutrients. 2020; 12(3):705. https://doi.org/10.3390/nu12030705
Chicago/Turabian StyleBarone, Michele, Eugenio Gemello, Maria Teresa Viggiani, Fernanda Cristofori, Caterina Renna, Andrea Iannone, Alfredo Di Leo, and Ruggiero Francavilla. 2020. "Evaluation of Non-Celiac Gluten Sensitivity in Patients with Previous Diagnosis of Irritable Bowel Syndrome: A Randomized Double-Blind Placebo-Controlled Crossover Trial" Nutrients 12, no. 3: 705. https://doi.org/10.3390/nu12030705