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The Role of Muscle Mass Gain Following Protein Supplementation Plus Exercise Therapy in Older Adults with Sarcopenia and Frailty Risks: A Systematic Review and Meta-Regression Analysis of Randomized Trials
Review

Efficacy of Nutritional Interventions as Stand-Alone or Synergistic Treatments with Exercise for the Management of Sarcopenia

1
Geriatric Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy
2
Phd Course in Nutritional Sciences, University of Milan, 20122 Milan, Italy
3
Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Nutrients 2019, 11(9), 1991; https://doi.org/10.3390/nu11091991
Received: 31 July 2019 / Revised: 20 August 2019 / Accepted: 20 August 2019 / Published: 23 August 2019
(This article belongs to the Special Issue Sarcopenia and Nutritional Status)
Sarcopenia is an age-related and accelerated process characterized by a progressive loss of muscle mass and strength/function. It is a multifactorial process associated with several adverse outcomes including falls, frailty, functional decline, hospitalization, and mortality. Hence, sarcopenia represents a major public health problem and has become the focus of intense research. Unfortunately, no pharmacological treatments are yet available to prevent or treat this age-related condition. At present, the only strategies for the management of sarcopenia are mainly based on nutritional and physical exercise interventions. The purpose of this review is, thus, to provide an overview on the role of proteins and other key nutrients, alone or in combination with physical exercise, on muscle parameters. View Full-Text
Keywords: sarcopenia; nutrition; physical exercise; synergism; older people sarcopenia; nutrition; physical exercise; synergism; older people
MDPI and ACS Style

Damanti, S.; Azzolino, D.; Roncaglione, C.; Arosio, B.; Rossi, P.; Cesari, M. Efficacy of Nutritional Interventions as Stand-Alone or Synergistic Treatments with Exercise for the Management of Sarcopenia. Nutrients 2019, 11, 1991. https://doi.org/10.3390/nu11091991

AMA Style

Damanti S, Azzolino D, Roncaglione C, Arosio B, Rossi P, Cesari M. Efficacy of Nutritional Interventions as Stand-Alone or Synergistic Treatments with Exercise for the Management of Sarcopenia. Nutrients. 2019; 11(9):1991. https://doi.org/10.3390/nu11091991

Chicago/Turabian Style

Damanti, Sarah, Domenico Azzolino, Carlotta Roncaglione, Beatrice Arosio, Paolo Rossi, and Matteo Cesari. 2019. "Efficacy of Nutritional Interventions as Stand-Alone or Synergistic Treatments with Exercise for the Management of Sarcopenia" Nutrients 11, no. 9: 1991. https://doi.org/10.3390/nu11091991

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