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Coffee Abundant in Chlorogenic Acids Reduces Abdominal Fat in Overweight Adults: A Randomized, Double-Blind, Controlled Trial

1
Biological Science Research Laboratories, Kao Corporation, 2-1-3 Bunka, Sumida, Tokyo 131-8501, Japan
2
Health Care Food Research Laboratories, Kao Corporation, 2-1-3 Bunka, Sumida, Tokyo 131-8501, Japan
3
Fukuhara Hospital, 3-1-15 Shimamatsuhigashimachi, Eniwa, Hokkaido 061-1351, Japan
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(7), 1617; https://doi.org/10.3390/nu11071617
Received: 11 June 2019 / Revised: 11 July 2019 / Accepted: 13 July 2019 / Published: 16 July 2019
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Abstract

The components of roasted or green coffee beans that promote abdominal fat reduction are not clear. We investigated the effects of daily consumption of coffee enriched in chlorogenic acids (CGA) on abdominal fat area in a randomized, double-blind, parallel controlled trial. Healthy, overweight men and women (n = 150, body mass index (BMI) ≥25 to <30 kg/m2) were randomly allocated to high-CGA (369 mg CGA/serving) or control (35 mg CGA/serving) coffee groups. Instant coffee was consumed once daily for 12 weeks, with four-week pre- and post-observation periods. Abdominal fat area and anthropometric measurements were analyzed at baseline and at four, eight, and 12 weeks, and 142 subjects completed the trial. Visceral fat area (VFA), total abdominal fat area (TFA), body weight, and waist circumference significantly decreased in the CGA group compared with the control group, with a group × time interaction (p < 0.001, p = 0.001, p = 0.025, and p = 0.001, respectively). Changes in VFA and TFA from baseline to 12 weeks were significantly greater in the CGA group than in the control group (−9.0 ± 13.9 cm2 vs. −1.0 ± 14.3 cm2, p < 0.001; −13.8 ± 22.9 cm2 vs. −2.0 ± 16.2 cm2, p < 0.001). No severe adverse events occurred. Consumption of high-CGA coffee for 12 weeks by overweight adults might lower VFA, TFA, BMI, and waist circumference. View Full-Text
Keywords: chlorogenic acids; instant coffee; randomized clinical trial; total fat area; visceral fat area chlorogenic acids; instant coffee; randomized clinical trial; total fat area; visceral fat area
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Watanabe, T.; Kobayashi, S.; Yamaguchi, T.; Hibi, M.; Fukuhara, I.; Osaki, N. Coffee Abundant in Chlorogenic Acids Reduces Abdominal Fat in Overweight Adults: A Randomized, Double-Blind, Controlled Trial. Nutrients 2019, 11, 1617.

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