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Open AccessArticle

Social Inequalities in Prenatal Folic Acid Supplementation: Results from the ELFE Cohort

1
INSERM, UMR1153 Center for Research in Epidemiology and StatisticS (CRESS), Research Team on Early Life Origins of Health (EAROH), 75004 Paris, France
2
Université de Paris, UMR1153 Center for Research in Epidemiology and StatisticS (CRESS), Research Team on Early Life Origins of Health (EAROH), 75004 Paris, France
3
Unité Mixte Inserm-Ined-EFS Elfe, Ined, 75020 Paris, France
4
INRA, U1125 Center for Research in Epidemiology and StatisticS (CRESS), Research Team on Early Life Origins of Health (EAROH), 75004 Paris, France
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(5), 1108; https://doi.org/10.3390/nu11051108
Received: 23 April 2019 / Revised: 10 May 2019 / Accepted: 15 May 2019 / Published: 18 May 2019
(This article belongs to the Special Issue Early Life Nutrition and Future Health)
Most professional and international organizations recommend folic acid supplementation for women planning pregnancy. Various studies have shown high levels of non-compliance with this recommendation. This study aimed to identify sociodemographic characteristics related to this compliance. The analyses were based on 16,809 women from the French nationwide ELFE cohort (Etude Longitudinale Française depuis l’Enfance). Folic acid supplementation was assessed at delivery, and sociodemographic characteristics were collected at two months postpartum. The association between sociodemographic characteristics and compliance with recommendations on folic acid supplementation (no supplementation, periconceptional supplementation, and supplementation only after the periconceptional period) was examined using multivariate multinomial logistic regression. Only 26% of French women received folic acid supplementation during the periconceptional period, 10% of women received supplementation after the periconceptional period, and 64% received no supplementation. Young maternal age, low education level, low family income, multiparity, single parenthood, maternal unemployment, maternal overweight, and smoking during pregnancy were related to lower likelihood of folic acid supplementation during the periconceptional period compared to no supplementation. These associations were not explained by unplanned pregnancy. Immigrant and underweight women were more likely to receive folic acid supplementation after the periconceptional period. Our study confirms great social disparities in France regarding the compliance with the recommendations on folic acid supplementation. View Full-Text
Keywords: folic acid supplementation; pregnancy; epidemiology; social inequalities folic acid supplementation; pregnancy; epidemiology; social inequalities
MDPI and ACS Style

Camier, A.; Kadawathagedara, M.; Lioret, S.; Bois, C.; Cheminat, M.; Dufourg, M.-N.; Charles, M.A.; de Lauzon-Guillain, B. Social Inequalities in Prenatal Folic Acid Supplementation: Results from the ELFE Cohort. Nutrients 2019, 11, 1108.

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