Next Article in Journal
Diet Supplemented with Antioxidant and Anti-Inflammatory Probiotics Improves Sperm Quality after Only One Spermatogenic Cycle in Zebrafish Model
Next Article in Special Issue
Effect of Tomato Nutrient Complex on Blood Pressure: A Double Blind, Randomized Dose–Response Study
Previous Article in Journal
A Selective Role of Dietary Anthocyanins and Flavan-3-ols in Reducing the Risk of Type 2 Diabetes Mellitus: A Review of Recent Evidence
Previous Article in Special Issue
Mechanisms of Carotenoid Intestinal Absorption: Where Do We Stand?
Open AccessReview

β-carotene in Obesity Research: Technical Considerations and Current Status of the Field

1
Department of Food Sciences and Human Nutrition, University of Illinois Urbana Champaign, Urbana, IL 61801, USA
2
Division of Nutritional Sciences, University of Illinois Urbana Champaign, Urbana, IL 61801, USA
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(4), 842; https://doi.org/10.3390/nu11040842
Received: 16 February 2019 / Revised: 2 April 2019 / Accepted: 6 April 2019 / Published: 13 April 2019
(This article belongs to the Special Issue Carotenoids and Human Health)
Over the past decades, obesity has become a rising health problem as the accessibility to high calorie, low nutritional value food has increased. Research shows that some bioactive components in fruits and vegetables, such as carotenoids, could contribute to the prevention and treatment of obesity. Some of these carotenoids are responsible for vitamin A production, a hormone-like vitamin with pleiotropic effects in mammals. Among these effects, vitamin A is a potent regulator of adipose tissue development, and is therefore important for obesity. This review focuses on the role of the provitamin A carotenoid β-carotene in human health, emphasizing the mechanisms by which this compound and its derivatives regulate adipocyte biology. It also discusses the physiological relevance of carotenoid accumulation, the implication of the carotenoid-cleaving enzymes, and the technical difficulties and considerations researchers must take when working with these bioactive molecules. Thanks to the broad spectrum of functions carotenoids have in modern nutrition and health, it is necessary to understand their benefits regarding to metabolic diseases such as obesity in order to evaluate their applicability to the medical and pharmaceutical fields. View Full-Text
Keywords: Vitamin A; adipocyte; β-carotene oxygenase 1 Vitamin A; adipocyte; β-carotene oxygenase 1
Show Figures

Figure 1

MDPI and ACS Style

Coronel, J.; Pinos, I.; Amengual, J. β-carotene in Obesity Research: Technical Considerations and Current Status of the Field. Nutrients 2019, 11, 842.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop