Next Article in Journal
A Short Study Exploring the Effect of the Glycaemic Index of the Diet on Energy intake and Salivary Steroid Hormones
Previous Article in Journal
Hop Compounds: Extraction Techniques, Chemical Analyses, Antioxidative, Antimicrobial, and Anticarcinogenic Effects
Open AccessReview

Probiotics: How Effective Are They in the Fight against Obesity?

by 1,†, 1,† and 1,2,*
1
Department of Basic Medical Sciences, College of Osteopathic Medicine, Western University of Health Sciences, Pomona, CA 91766, USA
2
Department of Health and Human Development, University of Suceava, Suceava 720229, Romania
*
Author to whom correspondence should be addressed.
Contributed equally to the work.
Nutrients 2019, 11(2), 258; https://doi.org/10.3390/nu11020258
Received: 14 December 2018 / Revised: 15 January 2019 / Accepted: 18 January 2019 / Published: 24 January 2019
Obesity has been associated with structural and functional changes in the gut microbiota. The abundance in, and diversity of, certain bacteria may favor energy harvest and metabolic pathways leading to obesity. Therefore, gut microbiota has become a potential target that can be manipulated to obtain optimal health. Probiotics have been shown to influence the composition of the gut microbiota, improve gut integrity, and restore the microbial shifts characteristic of obesity. Based on physical and biochemical parameters, metabolic and inflammatory markers, and alterations in gut microbe diversity, animal studies revealed beneficial results in obese models whereas the results in humans are sparse and inconsistent. Thus, the purpose of this review is to present evidence from animal studies and human clinical trials demonstrating the effects of various probiotic strains and their potential efficacy in improving obesity and associated metabolic dysfunctions. Furthermore, the review discusses current gaps in our understanding of how probiotics modulate gut microflora to protect against obesity. Finally, we propose future studies and methodological approaches that may shed light on the challenges facing the scientific community in deciphering the host–bacteria interaction in obesity. View Full-Text
Keywords: microbiota; inflammation; adiposity; lactobacillus; bifidobacterium microbiota; inflammation; adiposity; lactobacillus; bifidobacterium
MDPI and ACS Style

Mazloom, K.; Siddiqi, I.; Covasa, M. Probiotics: How Effective Are They in the Fight against Obesity? Nutrients 2019, 11, 258. https://doi.org/10.3390/nu11020258

AMA Style

Mazloom K, Siddiqi I, Covasa M. Probiotics: How Effective Are They in the Fight against Obesity? Nutrients. 2019; 11(2):258. https://doi.org/10.3390/nu11020258

Chicago/Turabian Style

Mazloom, Kiran; Siddiqi, Imran; Covasa, Mihai. 2019. "Probiotics: How Effective Are They in the Fight against Obesity?" Nutrients 11, no. 2: 258. https://doi.org/10.3390/nu11020258

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop