Next Article in Journal
Glycemic Index, Glycemic Load and Cancer Risk: An Updated Meta-Analysis
Previous Article in Journal
Agaricus blazei-Based Mushroom Extract Supplementation to Birch Allergic Blood Donors: A Randomized Clinical Trial
Open AccessArticle

Serum Phosphorus as a Risk Factor of Metabolic Syndrome in the Elderly in Taiwan: A Large-Population Cohort Study

by Yi-Han Jhuang 1,2, Tung-Wei Kao 2,3,4, Tao-Chun Peng 2,3,4, Wei-Liang Chen 2,3,4, Pi-Kai Chang 1,2,5 and Li-Wei Wu 2,3,4,*
1
Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan
2
Graduate School of Medicine, National Defense Medical Center, Taipei 114, Taiwan
3
Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan
4
Division of Geriatric Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan
5
Division of Colon and Rectal Surgery, Department of Surgery, Tri-Service General Hospital; National Defense Medical Center, Taipei 114, Taiwan
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(10), 2340; https://doi.org/10.3390/nu11102340
Received: 6 August 2019 / Revised: 14 September 2019 / Accepted: 19 September 2019 / Published: 2 October 2019
Background: The impact of serum phosphorus concentration on metabolic syndrome were limited. Therefore, this study aimed to explore the association between the serum phosphorus and incident metabolic syndrome in the elderly in Taiwan. Methods: We included 1491 participants who had health check-ups in the Tri-Service General Hospital for the period 2007 to 2015 and divided them based on age to assess the incidence of metabolic syndrome. We performed the COX regression model to explore the impact of serum phosphorus for metabolic syndrome, diabetes mellitus, and hypertension by an age-specific group. Results: Our result showed that higher serum phosphorus concentration was noted in the elderly in the baseline characteristics. In the group older than 60 years, serum phosphorus concentration was correlated with the incidence of metabolic syndrome (hazard ratios (HR) = 1.39, 95% CI 1.11–1.74) and diabetes mellitus (HR = 1.49, 95% CI 1.15–1.92) after adjustment. We further found the relationship between serum phosphorus and incidence of the components of metabolic syndrome, including higher waist circumference, high-density lipoprotein (HDL), serum triglyceride, and fast glucose. Conclusions: Our study might provide an epidemiological evidence that serum phosphorus was related with the incidence of metabolic syndrome in the elderly in Taiwan. View Full-Text
Keywords: serum phosphorus; metabolic syndrome; elderly serum phosphorus; metabolic syndrome; elderly
Show Figures

Figure 1

MDPI and ACS Style

Jhuang, Y.-H.; Kao, T.-W.; Peng, T.-C.; Chen, W.-L.; Chang, P.-K.; Wu, L.-W. Serum Phosphorus as a Risk Factor of Metabolic Syndrome in the Elderly in Taiwan: A Large-Population Cohort Study. Nutrients 2019, 11, 2340.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop