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Nutrients 2018, 10(9), 1249; https://doi.org/10.3390/nu10091249

Effects of Vegetable Proteins on Hypercholesterolemia and Gut Microbiota Modulation

1
Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milano, Italy
2
Centro Dislipidemie, A.S.S.T. Grande Ospedale Metropolitano Niguarda, 220162 Milano, Italy
*
Author to whom correspondence should be addressed.
Received: 8 August 2018 / Revised: 30 August 2018 / Accepted: 3 September 2018 / Published: 6 September 2018
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Abstract

Risk assessment tools, i.e., validated risk prediction algorithms, to estimate the patient’s 10-year risk of developing cardiovascular disease (CVD) should be used to identify high-risk people for primary prevention. Current evidence confirms that appropriate monitoring and control of risk factors either reduces the likelihood of CVD or slows down its progression. It is thus crucial that all health professionals make appropriate use of all the available intervention strategies to control risk factors: from dietary improvement and adequate physical activity to the use of functional foods, food supplements, and drugs. The gut microbiota, which encompasses 1 × 1014 resident microorganisms, has been recently recognized as a contributing factor in the development of human disease. This review examines the effect of both some vegetable food components belong to the “protein food group” and the underexploited protein-rich hempseed on cholesterolemia and gut microbiota composition. View Full-Text
Keywords: protein food group; cholesterol; microbiota; soybeans; lupins; peas; hempseed; functional food; LDL-receptor; PCSK9 protein food group; cholesterol; microbiota; soybeans; lupins; peas; hempseed; functional food; LDL-receptor; PCSK9
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Busnelli, M.; Manzini, S.; Sirtori, C.R.; Chiesa, G.; Parolini, C. Effects of Vegetable Proteins on Hypercholesterolemia and Gut Microbiota Modulation. Nutrients 2018, 10, 1249.

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