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Open AccessFeature PaperReview

Vitamin D Requirements for the Future—Lessons Learned and Charting a Path Forward

Cork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, T12 Y337 Cork, Ireland
Nutrients 2018, 10(5), 533; https://doi.org/10.3390/nu10050533
Received: 6 April 2018 / Revised: 19 April 2018 / Accepted: 23 April 2018 / Published: 25 April 2018
(This article belongs to the Special Issue Changing Times for Vitamin D and Health)
Estimates of dietary requirements for vitamin D or Dietary Reference Values (DRV) are crucial from a public health perspective in providing a framework for prevention of vitamin D deficiency and optimizing vitamin D status of individuals. While these important public health policy instruments were developed with the evidence-base and data available at the time, there are some issues that need to be clarified or considered in future iterations of DRV for vitamin D. This is important as it will allow for more fine-tuned and truer estimates of the dietary requirements for vitamin D and thus provide for more population protection. The present review will overview some of the confusion that has arisen in relation to the application and/or interpretation of the definitions of the Estimated Average Requirement (EAR) and Recommended Dietary Allowance (RDA). It will also highlight some of the clarifications needed and, in particular, how utilization of a new approach in terms of using individual participant-level data (IPD), over and beyond aggregated data, from randomised controlled trials with vitamin D may have a key role in generating these more fine-tuned and truer estimates, which is of importance as we move towards the next iteration of vitamin D DRVs. View Full-Text
Keywords: vitamin D requirements; Dietary Reference Values; individual participant data vitamin D requirements; Dietary Reference Values; individual participant data
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Cashman, K.D. Vitamin D Requirements for the Future—Lessons Learned and Charting a Path Forward. Nutrients 2018, 10, 533.

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