Next Article in Journal
Effect of Mixed Meal and Leucine Intake on Plasma Amino Acid Concentrations in Young Men
Next Article in Special Issue
Low Diversity of Human Milk Oligosaccharides is Associated with Necrotising Enterocolitis in Extremely Low Birth Weight Infants
Previous Article in Journal
Objective Understanding of Front-of-Package Nutrition Labels: An International Comparative Experimental Study across 12 Countries
Previous Article in Special Issue
Microbiota and Derived Parameters in Fecal Samples of Infants with Non-IgE Cow’s Milk Protein Allergy under a Restricted Diet
Open AccessReview

Microbial and Nutritional Programming—The Importance of the Microbiome and Early Exposure to Potential Food Allergens in the Development of Allergies

Immunology Laboratory, Department of Pathology, The Children’s Memorial Health Institute, Aleja Dzieci Polskich 20, 04-730 Warsaw, Poland
Nutrients 2018, 10(10), 1541; https://doi.org/10.3390/nu10101541
Received: 30 September 2018 / Revised: 15 October 2018 / Accepted: 16 October 2018 / Published: 18 October 2018
(This article belongs to the Special Issue Probiotics and Prebiotics in Pediatrics)
The “microbiota hypothesis” ties the increase in allergy rates observed in highly developed countries over the last decades to disturbances in the gut microbiota. Gut microbiota formation depends on a number of factors and occurs over approximately 1000 days of life, including the prenatal period. During this period the microbiota helps establish the functional immune phenotype, including immune tolerance. The development of immune tolerance depends also on early exposure to potential food allergens, a process referred to as nutritional programming. This article elaborates on the concepts of microbial and nutritional programming and their role in the primary prevention of allergy. View Full-Text
Keywords: microbiome; intestinal microbiota; microbial programming; nutritional programming; allergy; prevention microbiome; intestinal microbiota; microbial programming; nutritional programming; allergy; prevention
Show Figures

Figure 1

MDPI and ACS Style

Cukrowska, B. Microbial and Nutritional Programming—The Importance of the Microbiome and Early Exposure to Potential Food Allergens in the Development of Allergies. Nutrients 2018, 10, 1541.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop