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Sustainability 2016, 8(11), 1131;

Bioactivity of Phycocolloids against the Mediterranean Protozoan Leishmania infantum: An Inceptive Study

CNR-ISMAR, Institute of Marine Sciences, Arsenale 101-104, Castello 2737F, 30122 Venice, Italy
Department of Environmental Sciences, Informatics and Statistics, University Ca’ Foscari Venice, Dorsoduro 2137, 30123 Venice, Italy
Centro di Referenza Nazionale per le Leishmaniosi (C.Re.Na.L.), Istituto Zooprofilattico Sperimentale della Sicilia, Viale Gino Marinuzzi 3, 90129 Palermo, Italy
Department of Biological and Environmental Sciences (Botany), University of Messina, Salita Sperone 31, 98166 Messina, Italy
Author to whom correspondence should be addressed.
Academic Editor: Vincenzo Torretta
Received: 8 September 2016 / Revised: 23 October 2016 / Accepted: 27 October 2016 / Published: 4 November 2016
(This article belongs to the Section Sustainable Use of the Environment and Resources)
Full-Text   |   PDF [1226 KB, uploaded 4 November 2016]   |  


Sulfated polysaccharides from marine macroalgae have been shown to possess a variety of biological activities against fungi, bacteria, viruses, and protozoa. In this study, the in vitro activity of algal polysaccharides against Leishmania infantum (Kinetoplastida: Trypanosomatidae) was investigated. The polysaccharides were extracted from different macroalgae of the Mediterranean Sea: Chaetomorpha linum, Agardhiella subulata, Gracilaria viridis, Gracilaria bursa-pastoris, Hypnea cornuta, Sargassum muticum, and Undaria pinnatifida. Preliminary results showed a good anti-leishmanial activity of the investigated species, encouraging the focus on their use as natural resources in order to match integrated management strategies for the employment of local macroalgae. View Full-Text
Keywords: seaweeds; phycocolloids; Leishmania infantum seaweeds; phycocolloids; Leishmania infantum

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Armeli Minicante, S.; Michelet, S.; Bruno, F.; Castelli, G.; Vitale, F.; Sfriso, A.; Morabito, M.; Genovese, G. Bioactivity of Phycocolloids against the Mediterranean Protozoan Leishmania infantum: An Inceptive Study. Sustainability 2016, 8, 1131.

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