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Clinics and Practice
Volume 12
Issue 5
10.3390/clinpract12050076
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Case Report

Efficacy of Naproxen/Fexofenadine (SJP-003) in the Prevention of Side Effects of Influenza Vaccination: Four Case Studies

by
Pantea Kiani
1,
Thomas A. Dahl
2,
Jacqueline M. Iversen
2,*,
Andrew Scholey
3 and
Joris C. Verster
1,4
1
Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3584CG Utrecht, The Netherlands
2
Sen-Jam Pharmaceutical, 223 Wall St., #130, Huntington, NY 11743, USA
3
Nutrition Dietetics and Food, School of Clinical Sciences, Monash University, Melbourne, VIC 3168, Australia
4
Centre for Human Psychopharmacology, Swinburne University, Melbourne, VIC 3122, Australia
*
Author to whom correspondence should be addressed.
Clin. Pract. 2022, 12(5), 734-737; https://doi.org/10.3390/clinpract12050076
Submission received: 10 June 2022 / Revised: 2 August 2022 / Accepted: 7 September 2022 / Published: 9 September 2022
Versions Notes

Abstract

The influenza virus is associated with sickness, and in particular among vulnerable populations such as elderly and those with underlying disease with hospitalization and increased mortality rates. Vaccination is an effective way to prevent infection with influenza. However, undesirable side effects of the vaccination are commonly experienced, and comprise one of the primary reasons for a substantial group of individuals to refrain from vaccination. An effective treatment against vaccination side effects could increase the overall willingness to vaccinate against influenza. Here, four cases are presented that self-administered SJP-003 (a combination of 220 mg naproxen sodium, directly followed by a single oral dose of 60 mg fexofenadine HCL), 2 h before and 10 h after influenza vaccination. No flu-like symptoms and pain at the injection site were reported. These observations warrant further investigation of SJP-003 in double-blind, placebo-controlled clinical trials.
Keywords: influenza; vaccination; side effects; pain at injection site; flu-like symptoms; naproxen; fexofenadine; SJP-003; willingness to vaccinate influenza; vaccination; side effects; pain at injection site; flu-like symptoms; naproxen; fexofenadine; SJP-003; willingness to vaccinate

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MDPI and ACS Style

Kiani, P.; Dahl, T.A.; Iversen, J.M.; Scholey, A.; Verster, J.C. Efficacy of Naproxen/Fexofenadine (SJP-003) in the Prevention of Side Effects of Influenza Vaccination: Four Case Studies. Clin. Pract. 2022, 12, 734-737. https://doi.org/10.3390/clinpract12050076

AMA Style

Kiani P, Dahl TA, Iversen JM, Scholey A, Verster JC. Efficacy of Naproxen/Fexofenadine (SJP-003) in the Prevention of Side Effects of Influenza Vaccination: Four Case Studies. Clinics and Practice. 2022; 12(5):734-737. https://doi.org/10.3390/clinpract12050076

Chicago/Turabian Style

Kiani, Pantea, Thomas A. Dahl, Jacqueline M. Iversen, Andrew Scholey, and Joris C. Verster. 2022. "Efficacy of Naproxen/Fexofenadine (SJP-003) in the Prevention of Side Effects of Influenza Vaccination: Four Case Studies" Clinics and Practice 12, no. 5: 734-737. https://doi.org/10.3390/clinpract12050076

APA Style

Kiani, P., Dahl, T. A., Iversen, J. M., Scholey, A., & Verster, J. C. (2022). Efficacy of Naproxen/Fexofenadine (SJP-003) in the Prevention of Side Effects of Influenza Vaccination: Four Case Studies. Clinics and Practice, 12(5), 734-737. https://doi.org/10.3390/clinpract12050076

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