Next Article in Journal
COVID-19: Hemoglobin, Iron, and Hypoxia beyond Inflammation. A Narrative Review
Previous Article in Journal
Early Intervention versus Standard of Care for Mild Idiopathic Scoliosis: A Case-Controlled Series Based on Sosort Criteria Evaluating the Impact of a Scoliosis Activity Suit
Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
Case Report

Keratinocyte Dissociation (Desmolysis/Acantholysis) in Ameloblastoma

1
Department of Oral Pathology and Microbiology, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Sant-Tukaram Nagar, Pimpri, Pune, MH, India
2
Department of Oral Medicine and Radiology, KLE’s Institute of Dental Sciences, Bangalore, India
3
Department of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan, Saudi Arabia
*
Author to whom correspondence should be addressed.
Clin. Pract. 2020, 10(2), 31-33; https://doi.org/10.4081/cp.2020.1255
Received: 18 April 2020 / Revised: 26 April 2020 / Accepted: 18 May 2020 / Published: 19 May 2020
Ameloblastoma is the only odontogenic tumor that displays diversified histomorphological features with subtypes like follicular, plexiform, acanthomatous, granular cell, clear cell, desmoplastic etc. In this paper we presented an extremely unusual presentation of ameloblastoma, which is characterized by desmolysis or acantholysis of stellate reticulum-like cells caused due to keratinocyte dissociation. A 35-year-old male patient presented with a painless hard 3×3 cm swelling in the mandibular right posterior region in the past 4-5 months. Radiographic examination revealed a multilocular radiolucent lesion in the body of mandible with resorption of the roots. Histopathological examination revealed ameloblastic follicles with central cells showing keratinocyte dissociation leading to desmolysis/acantholysis. Desmolytic cells were seen as an isolated entity in the follicular space with round to polygonal shaped morphology. Future retrospective studies on archival samples of ameloblastoma are recommended to relook into identification of such rare phenomenon. This will help in better understanding of the incidence rate and biological behavior of this rare variant of ameloblastoma.
Keywords: ameloblastoma; odontogenic tumor; jaw tumor; desmolysis; acantholysis ameloblastoma; odontogenic tumor; jaw tumor; desmolysis; acantholysis
MDPI and ACS Style

Sarode, S.C.; Sarode, G.S.; Birur, P.; Alhazmi, Y.A.; Patil, S. Keratinocyte Dissociation (Desmolysis/Acantholysis) in Ameloblastoma. Clin. Pract. 2020, 10, 31-33. https://doi.org/10.4081/cp.2020.1255

AMA Style

Sarode SC, Sarode GS, Birur P, Alhazmi YA, Patil S. Keratinocyte Dissociation (Desmolysis/Acantholysis) in Ameloblastoma. Clinics and Practice. 2020; 10(2):31-33. https://doi.org/10.4081/cp.2020.1255

Chicago/Turabian Style

Sarode, Sachin C., Gargi S. Sarode, Praveen Birur, Yaser A. Alhazmi, and Shankargouda Patil. 2020. "Keratinocyte Dissociation (Desmolysis/Acantholysis) in Ameloblastoma" Clinics and Practice 10, no. 2: 31-33. https://doi.org/10.4081/cp.2020.1255

Find Other Styles

Article Access Map by Country/Region

1
Back to TopTop