Next Article in Journal
Transient Loss of Consciousness in a Patient with a Brugada Like ECG
Previous Article in Journal
Odontogenic Myxoma of the Maxilla
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Clinics and Practice
Volume 1
Issue 4
10.4081/cp.2011.e125
clinpract-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Multiple Sclerosis in an Adrenoleukodystrophy Carrier

by
Thomas Jenkins
1,2,
Priya Sarasamma
1,
Godfrey Gillett
3,
Stuart Coley
4 and
Basil Sharrack
1,2,*
1
Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK
2
Sheffield Institute for Translational Neuroscience, Royal Hallamshire Hospital, Sheffield, UK
3
Department of Clinical Chemistry, Royal Hallamshire Hospital, Sheffield, UK
4
Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield, UK
*
Author to whom correspondence should be addressed.
Clin. Pract. 2011, 1(4), e125; https://doi.org/10.4081/cp.2011.e125
Submission received: 26 October 2011 / Revised: 26 October 2011 / Accepted: 15 November 2011 / Published: 30 November 2011

Abstract

X-linked adrenoleukodystrophy (X-ALD) is a rare inherited metabolic disorder, in which accumulation of very long chain fatty acids (VLCFAs) results in damage to the central nervous system. As the disease is X-linked, males are affected severely, but female carriers may also present with neurological symptoms. We report the case of a young adult female, who presented with episodic sensorimotor symptoms. Although she was a heterozygous female carrier of X-ALD, subsequent investigations confirmed a diagnosis of multiple sclerosis (MS). To the best of our knowledge, this is the first reported case of a female X-ALD carrier in which the clinical features were more consistent with co-existent MS than ALD-related pathology. The case serves as a reminder that alternative, more common diagnoses should also be considered in carriers of rare neurological syndromes.
Keywords: multiple sclerosis; adrenoleukodystrophy multiple sclerosis; adrenoleukodystrophy

Share and Cite

MDPI and ACS Style

Jenkins, T.; Sarasamma, P.; Gillett, G.; Coley, S.; Sharrack, B. Multiple Sclerosis in an Adrenoleukodystrophy Carrier. Clin. Pract. 2011, 1, e125. https://doi.org/10.4081/cp.2011.e125

AMA Style

Jenkins T, Sarasamma P, Gillett G, Coley S, Sharrack B. Multiple Sclerosis in an Adrenoleukodystrophy Carrier. Clinics and Practice. 2011; 1(4):e125. https://doi.org/10.4081/cp.2011.e125

Chicago/Turabian Style

Jenkins, Thomas, Priya Sarasamma, Godfrey Gillett, Stuart Coley, and Basil Sharrack. 2011. "Multiple Sclerosis in an Adrenoleukodystrophy Carrier" Clinics and Practice 1, no. 4: e125. https://doi.org/10.4081/cp.2011.e125

APA Style

Jenkins, T., Sarasamma, P., Gillett, G., Coley, S., & Sharrack, B. (2011). Multiple Sclerosis in an Adrenoleukodystrophy Carrier. Clinics and Practice, 1(4), e125. https://doi.org/10.4081/cp.2011.e125

Article Metrics

Back to TopTop