Next Article in Journal
Content Validity of the CHANT’s French-Language Translation and Cultural Adaptation: A Modified E-Delphi Study
Previous Article in Journal
Nursing Roles and Responsibilities in Outpatient Bronchiectasis Care: A Scoping Review
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Sexual Functioning and Patient-Reported Concerns After Stroke: An Integrated Mixed-Methods Study in Clinical Rehabilitation

by
Alfredo Manuli
1,
Maria Grazia Maggio
2,*,
Andrea Calderone
2,
Lilla Bonanno
2,
Provvidenza Tomasello
2,
Caterina Pucci
3,
Morena De Francesco
4,
Gianluca Pucciarelli
1,† and
Rocco Salvatore Calabrò
2,†
1
Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy
2
IRCCS Centro Neurolesi Bonino-Pulejo, S.S. 113 Via Palermo, C. da Casazza, 98124 Messina, Italy
3
S. Anna Institute, Via Siris 11, 88900 Crotone, Italy
4
Institute of Bioimaging and Complex Biological Systems (IBSBC), National Research Council of Italy (CNR), 88100 Catanzaro, Italy
*
Author to whom correspondence should be addressed.
These authors contributed equally as senior authors.
Nurs. Rep. 2026, 16(7), 243; https://doi.org/10.3390/nursrep16070243
Submission received: 13 May 2026 / Revised: 13 July 2026 / Accepted: 14 July 2026 / Published: 14 July 2026

Abstract

Background/Objectives: Sexual health is frequently under-addressed after stroke, despite its relevance to intimacy, identity, relationships, and rehabilitation. This convergent mixed-methods study integrated sex-specific screening with descriptive narrative material to examine sexual functioning and patient-reported concerns in clinical rehabilitation. Methods: Twenty-six adults were assessed: ten with the Female Sexual Function Index (FSFI), sixteen with an International Index of Erectile Function six-item field (IIEF-6), and ten with analyzable semi-structured interview responses. The sex-specific measures were analyzed separately. Continuous variables were summarized by median and interquartile range; nonparametric correlations and group comparisons underwent Benjamini–Hochberg false discovery rate correction. Quantitative and qualitative findings were integrated in a participant-level joint display. This integration yielded case-level meta-inferences rather than inferential mixed-methods testing in this sample. Results: Nine of ten FSFI profiles and nine of sixteen IIEF-6 profiles met the respective exploratory threshold for possible dysfunction. No association or group comparison remained statistically significant after correction. Six of eighteen threshold-positive profiles had analyzable interviews, twelve represented narrative silence, and four interviewed participants were threshold-negative. Narratives documented fear, embarrassment, reduced desire or sexual frequency, relational or communication change, support needs, clinical sequelae, and positive or neutral adaptation. Screening and narratives showed convergence, complementarity, and divergence: low scores did not establish personal distress, whereas concerns could occur above a threshold. Conclusions: Responsive sexual rehabilitation should combine confidential, permission-based, patient-led screening and narrative inquiry with individualized information, optional support, appropriate referral, and reassessment according to readiness. These preliminary, hypothesis-generating findings do not validate an intervention or support confirmatory inference.
Keywords: stroke; sexual function; sexual health; rehabilitation; mixed-methods; nursing; quality of life; depression; relationship functioning stroke; sexual function; sexual health; rehabilitation; mixed-methods; nursing; quality of life; depression; relationship functioning
Graphical Abstract

Share and Cite

MDPI and ACS Style

Manuli, A.; Maggio, M.G.; Calderone, A.; Bonanno, L.; Tomasello, P.; Pucci, C.; De Francesco, M.; Pucciarelli, G.; Calabrò, R.S. Sexual Functioning and Patient-Reported Concerns After Stroke: An Integrated Mixed-Methods Study in Clinical Rehabilitation. Nurs. Rep. 2026, 16, 243. https://doi.org/10.3390/nursrep16070243

AMA Style

Manuli A, Maggio MG, Calderone A, Bonanno L, Tomasello P, Pucci C, De Francesco M, Pucciarelli G, Calabrò RS. Sexual Functioning and Patient-Reported Concerns After Stroke: An Integrated Mixed-Methods Study in Clinical Rehabilitation. Nursing Reports. 2026; 16(7):243. https://doi.org/10.3390/nursrep16070243

Chicago/Turabian Style

Manuli, Alfredo, Maria Grazia Maggio, Andrea Calderone, Lilla Bonanno, Provvidenza Tomasello, Caterina Pucci, Morena De Francesco, Gianluca Pucciarelli, and Rocco Salvatore Calabrò. 2026. "Sexual Functioning and Patient-Reported Concerns After Stroke: An Integrated Mixed-Methods Study in Clinical Rehabilitation" Nursing Reports 16, no. 7: 243. https://doi.org/10.3390/nursrep16070243

APA Style

Manuli, A., Maggio, M. G., Calderone, A., Bonanno, L., Tomasello, P., Pucci, C., De Francesco, M., Pucciarelli, G., & Calabrò, R. S. (2026). Sexual Functioning and Patient-Reported Concerns After Stroke: An Integrated Mixed-Methods Study in Clinical Rehabilitation. Nursing Reports, 16(7), 243. https://doi.org/10.3390/nursrep16070243

Article Metrics

Back to TopTop