Comparing Slim Straight and Slim Perimodiolar Electrode Arrays for Cochlear Implantation: Hearing Results and Risks—A Systematic Review (2015–2025)
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Eligibility Criteria (PICO Framework)
- Population: Pediatric or adult patients undergoing primary cochlear implantation
- Intervention: Perimodiolar electrode arrays
- Comparison: Straight (lateral wall) electrode arrays
- Outcomes:
- ○
- Primary: Speech perception scores (e.g., CNC words, monosyllables, and sentence recognition)
- ○
- Secondary: Residual hearing preservation, scalar position, scalar translocation, tip fold-over, and electrode migration
- Study types: Randomized controlled trials, cohort studies, comparative observational studies, and systematic reviews
- Publication years: 2015–2025
- Language: English
2.3. Information Sources and Search Strategy
2.4. Study Selection
2.5. Data Extraction
2.6. Risk of Bias Assessment
3. Results
3.1. Study Selection
3.2. Study Characteristics
3.3. Hearing Outcomes
3.3.1. Speech Perception
3.3.2. Residual Hearing Preservation
3.3.3. Scalar Translocation
3.3.4. Tip Fold-Over
3.3.5. Electrode Migration
| Slim Straight (e.g., CI422/CI522) | Slim Perimodiolar (e.g., CI532/CI632) | Key Reference | |
|---|---|---|---|
| Placement | Rests along the lateral wall | Hugs the inner wall Lower current levels and more Targeted stimulation is possible When the nerve is closer | |
| Stimulation Efficiency Speech Perception | Wider current spread, requires more power because it is further from the neural targets Excellent, comparable to SME in quiet and noise Excellent; comparable to PM in quiet and noise. | Lower current levels and more targeted stimulation are possible when the nerve is closer Lower thresholds; better frequency selectivity. | |
| Hearing Preservation | Traditionally superior; rates ~53–82%, but often shows a decline after 12 months (56%) | Improving with “Slim” designs; nearly unchanged rates ~59%. | [34,35] |
| Translocation Risk | Lower risk of scalar deviation (<10%). | Higher historical risk (up to 20%); Slim PM < 10%. | [36,37] |
| Insertion Trauma | Higher risk of damage to the basilar membrane due to its lateral position. | Higher risk of tip fold-over (~3.7–5%). | [36,38] |
4. Discussion
5. Limitations
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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| ROBINS-I Domain | Risk Level |
|---|---|
| Bias due to confounding | Moderate |
| Bias in selection of participants | Low |
| Bias in classification of interventions | Low |
| Bias due to deviations from intended interventions | Low |
| Bias due to missing data | Moderate |
| Bias in measurement of outcomes | Low |
| Bias in selection of reported results | Moderate |
| Overall risk of bias | Moderate |
| No. | First Author | Year | Journal | Study Design | Electrode Type Compared | Ref No. |
|---|---|---|---|---|---|---|
| 1 | Dhanasingh | 2017 | Hearing Research | Narrative review | LW vs. PM | [1] |
| 2 | O’Connell | 2016 | Otology & Neurotology | Retrospective cohort | CI522 vs. CI512 | [2] |
| 3 | Jwair | 2021 | Laryngoscope | Meta-analysis | LW vs. PM | [3] |
| 4 | Ketterer | 2022 | Eur Arch Otorhinolaryngol | Retrospective cohort | LW vs. PM | [4] |
| 5 | Shaul | 2018 | J Laryngol Otol | Retrospective cohort | PM only | [5] |
| 6 | Ramos de Miguel | 2022 | J Clin Med | Temporal bone study | Slim PM | [6] |
| 7 | Giardina | 2019 | Ear Hear | Prospective cohort | Flexible LW | [7] |
| 8 | Zimmermann | 2025 | J Otolaryngol Head Neck Surg | Systematic review | LW vs. PM | [8] |
| 9 | MacPhail | 2022 | Otolaryngol Head Neck Surg | Retrospective cohort | Slim straight vs. slim modiolar | [9] |
| 10 | Pennington-FitzGerald | 2025 | Otolaryngol Head Neck Surg | Retrospective cohort | LW vs. PM | [10] |
| 11 | Fries | 2025 | Front Neurol | Retrospective cohort | LW vs. PM | [11] |
| 12 | Almuhawas | 2025 | Eur Arch Otorhinolaryngol | Prospective cohort | PM | [12] |
| 13 | Garaycochea | 2020 | Eur Arch Otorhinolaryngol | Comparative cohort | 2 PM vs. 1 LW | [13] |
| 14 | O’Connell | 2016 | Laryngoscope Investig Otolaryngol | Review | LW vs. PM | [14] |
| 15 | Mewes | 2020 | Otology & Neurotology | Comparative cohort | PM designs | [15] |
| 16 | Zarowski | 2020 | Eur Arch Otorhinolaryngol | Pediatric cohort | LW vs. PM | [16] |
| 17 | Wanna | 2015 | Otology & Neurotology | Prospective cohort | LW vs. PM | [17] |
| 18 | Helbig | 2015 | Otology & Neurotology | Prospective cohort | Flexible LW | [18] |
| 19 | Shew | 2021 | Otology & Neurotology | Retrospective cohort | Slim modiolar | [19] |
| 20 | Hallin | 2024 | Acta Otolaryngologica | Retrospective cohort | LW vs. PM | [20] |
| 21 | Woodson | 2020 | Otology & Neurotology | Comparative cohort | Slim PM vs. slim LW | [21] |
| 22 | Liebscher | 2021 | Z Med Phys | Retrospective cohort | PM | [22] |
| 23 | Patro | 2024 | Otology & Neurotology | Comparative cohort | Mid-scala vs. LW | [23] |
| 24 | Varghese | 2024 | Otolaryngol Head Neck Surg | Retrospective cohort | Slim PM | [24] |
| 25 | Savoca | 2023 | Otolaryngol Head Neck Surg | Retrospective cohort | PM | [25] |
| 26 | Chabuz | 2025 | Laryngoscope | Cadaver study | PM | [26] |
| 27 | Zuniga | 2017 | Otology & Neurotology | Case series | PM | [27] |
| 28 | Dhanasingh | 2024 | Front Neurol | Narrative review | CI electrode designs | [28] |
| 29 | Gabrielpillai | 2018 | Otology & Neurotology | Retrospective cohort | Slim PM | [29] |
| 30 | von Mitzlaff | 2021 | Cochlear Implants Int | Retrospective cohort | LW | [30] |
| 31 | Magos | 2024 | Cochlear Implants Int | Retrospective cohort | LW vs. PM | [31] |
| 32 | Ha | 2024 | Eur Arch Otorhinolaryngol | Experimental study | Fixation techniques | [32] |
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Jang, C.H.; Kim, D.Y. Comparing Slim Straight and Slim Perimodiolar Electrode Arrays for Cochlear Implantation: Hearing Results and Risks—A Systematic Review (2015–2025). Audiol. Res. 2026, 16, 28. https://doi.org/10.3390/audiolres16010028
Jang CH, Kim DY. Comparing Slim Straight and Slim Perimodiolar Electrode Arrays for Cochlear Implantation: Hearing Results and Risks—A Systematic Review (2015–2025). Audiology Research. 2026; 16(1):28. https://doi.org/10.3390/audiolres16010028
Chicago/Turabian StyleJang, Chul Ho, and Do Yeon Kim. 2026. "Comparing Slim Straight and Slim Perimodiolar Electrode Arrays for Cochlear Implantation: Hearing Results and Risks—A Systematic Review (2015–2025)" Audiology Research 16, no. 1: 28. https://doi.org/10.3390/audiolres16010028
APA StyleJang, C. H., & Kim, D. Y. (2026). Comparing Slim Straight and Slim Perimodiolar Electrode Arrays for Cochlear Implantation: Hearing Results and Risks—A Systematic Review (2015–2025). Audiology Research, 16(1), 28. https://doi.org/10.3390/audiolres16010028
