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Hematology Reports
Volume 13
Issue 2
10.4081/hr.2021.8847
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Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Long-Term and Quality of Survival in Patients Treated for Acute Lymphoblastic Leukemia during the Pediatric Age

by
Lara Devilli
*,
Chiara Garonzi
,
Rita Balter
,
Elisa Bonetti
,
Matteo Chinello
,
Ada Zaccaron
,
Virginia Vitale
,
Massimiliano De Bortoli
,
Giulia Caddeo
,
Valentina Baretta
,
Gloria Tridello
and
Simone Cesaro
Pediatric Hematology Oncology, Department of Mother and Child, Azienda Ospedaliera Universitaria Integrata, 37126 Verona, Italy
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2021, 13(2), 8847; https://doi.org/10.4081/hr.2021.8847
Submission received: 18 August 2020 / Revised: 29 September 2020 / Accepted: 30 October 2020 / Published: 5 March 2021

Abstract

Long-term survival for acute lymphoblastic leukemia (ALL) in children improved over the last three decades up to 80–90% of affected patients. Consequently, the quality of life of survivors has become increasingly important. This study analyses the clinical features and outcome of 119 children with ALL, focusing on the quality of long-term survival in a subset of 22 patients over 18 years of age. Among this group, the 10-year event-free survival and overall survival were 83.1% (C.I. 74.0–89.2) and 88.4% (C.I. 80.9–93.1), respectively. Treatment related long-term medical complications were reported only in 2 patients (9.1%). Secondary school was completed successfully in 20 of 22 patients (89.9%). The remaining 2 patients were still attending at the time of the analysis. In conclusion, current treatment for ALL is well tolerated and does not compromise significantly the quality of life of survivors.
Keywords: acute lymphoblastic leukemia; pediatric leukemia; survival acute lymphoblastic leukemia; pediatric leukemia; survival

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MDPI and ACS Style

Devilli, L.; Garonzi, C.; Balter, R.; Bonetti, E.; Chinello, M.; Zaccaron, A.; Vitale, V.; De Bortoli, M.; Caddeo, G.; Baretta, V.; et al. Long-Term and Quality of Survival in Patients Treated for Acute Lymphoblastic Leukemia during the Pediatric Age. Hematol. Rep. 2021, 13, 8847. https://doi.org/10.4081/hr.2021.8847

AMA Style

Devilli L, Garonzi C, Balter R, Bonetti E, Chinello M, Zaccaron A, Vitale V, De Bortoli M, Caddeo G, Baretta V, et al. Long-Term and Quality of Survival in Patients Treated for Acute Lymphoblastic Leukemia during the Pediatric Age. Hematology Reports. 2021; 13(2):8847. https://doi.org/10.4081/hr.2021.8847

Chicago/Turabian Style

Devilli, Lara, Chiara Garonzi, Rita Balter, Elisa Bonetti, Matteo Chinello, Ada Zaccaron, Virginia Vitale, Massimiliano De Bortoli, Giulia Caddeo, Valentina Baretta, and et al. 2021. "Long-Term and Quality of Survival in Patients Treated for Acute Lymphoblastic Leukemia during the Pediatric Age" Hematology Reports 13, no. 2: 8847. https://doi.org/10.4081/hr.2021.8847

APA Style

Devilli, L., Garonzi, C., Balter, R., Bonetti, E., Chinello, M., Zaccaron, A., Vitale, V., De Bortoli, M., Caddeo, G., Baretta, V., Tridello, G., & Cesaro, S. (2021). Long-Term and Quality of Survival in Patients Treated for Acute Lymphoblastic Leukemia during the Pediatric Age. Hematology Reports, 13(2), 8847. https://doi.org/10.4081/hr.2021.8847

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