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Pediatric Reports
Volume 9
Issue 4
10.4081/pr.2017.7341
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Case Report

Zika Virus Infection in a Pediatric Patient With Acute Gastrointestinal Involvement

by
Svetoslav Slavov
1,*,
Alessandra Matsuno
1,
Aparecida Yamamoto
2,
Katia Otaguiri
1,
Maria Cervi
2,
Dimas Covas
1 and
Simone Kashima
3
1
Blood Center of Ribeirão Preto, Faculty of Medicine of Ribeirão Preto; Department of Internal Medicine, Faculty of Medicine of Ribeirão Preto, Brazil
2
Department of Pediatrics, Faculty of Medicine of Ribeirão Preto, Brazil
3
Blood Center of Ribeirão Preto, Faculty of Medicine of Ribeirão Preto; Department of Clinical, Toxicological and Bromatological Analyses, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Brazil
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2017, 9(4), 7341; https://doi.org/10.4081/pr.2017.7341
Submission received: 3 August 2017 / Revised: 3 August 2017 / Accepted: 20 October 2017 / Published: 3 January 2018

Abstract

Zika virus (ZIKV) is a mosquito-borne flavivirus, which has been related to severe neurological complications in neonates. However, many clinical aspects of the infection remain unclear, especially in pediatric patients. In this case report we describe the uncommon presentation of ZIKV infection in a pediatric patient with acute gastrointestinal involvement hospitalized in a Brazilian Emergency Unit. Dengue hemorrhagic fever was initially suspected, however, the molecular result for Dengue was negative. Molecular testing for other arboviruses (ZIKV and Chikungunya), revealed positive for ZIKV RNA result in both blood and saliva. The ZIKV load in saliva (6.947 copies/mL) was higher than the vetected ZIKV RNA in plasma (1.945 copies/mL). Additionally, the performed abdominal ultrasound revealed mesenteric lymphadenitis without abdominal retention of fluids. The presentation of this case demonstrates that ZIKV can be involved in a broader range of clinical conditions than currently assumed, including pediatric emergencies, especially in regions with extensive ZIKV outbreaks.
Keywords: Zika virus; ZIKV; Abdominal pain; Viral load Zika virus; ZIKV; Abdominal pain; Viral load

Share and Cite

MDPI and ACS Style

Slavov, S.; Matsuno, A.; Yamamoto, A.; Otaguiri, K.; Cervi, M.; Covas, D.; Kashima, S. Zika Virus Infection in a Pediatric Patient With Acute Gastrointestinal Involvement. Pediatr. Rep. 2017, 9, 7341. https://doi.org/10.4081/pr.2017.7341

AMA Style

Slavov S, Matsuno A, Yamamoto A, Otaguiri K, Cervi M, Covas D, Kashima S. Zika Virus Infection in a Pediatric Patient With Acute Gastrointestinal Involvement. Pediatric Reports. 2017; 9(4):7341. https://doi.org/10.4081/pr.2017.7341

Chicago/Turabian Style

Slavov, Svetoslav, Alessandra Matsuno, Aparecida Yamamoto, Katia Otaguiri, Maria Cervi, Dimas Covas, and Simone Kashima. 2017. "Zika Virus Infection in a Pediatric Patient With Acute Gastrointestinal Involvement" Pediatric Reports 9, no. 4: 7341. https://doi.org/10.4081/pr.2017.7341

APA Style

Slavov, S., Matsuno, A., Yamamoto, A., Otaguiri, K., Cervi, M., Covas, D., & Kashima, S. (2017). Zika Virus Infection in a Pediatric Patient With Acute Gastrointestinal Involvement. Pediatric Reports, 9(4), 7341. https://doi.org/10.4081/pr.2017.7341

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