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Case Report

Successful Use of Antihistamines in Severe Hypereosinophilia

by
Stefano Vallero
*,
Anna Mondino
,
Loredana Farinasso
,
Giulia Ansaldi
,
Mirella Davitto
and
Ugo Ramenghi
Hematology Unit, Pediatric Department, Children's Hospital Regina Margherita, Turin, Italy
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2012, 4(3), e26; https://doi.org/10.4081/pr.2012.e26
Submission received: 27 January 2012 / Accepted: 12 February 2012 / Published: 22 June 2012

Abstract

Eosinophilia is common in childhood, and in most cases it is mild and of limited clinical relevance, being often secondary to allergy or infections. In rare cases, eosinophilia may be idiopathic or related to neoplastic aetiology. When severe and protracted, it can cause potentially irreversible organ or system damage, whose prevention is the first priority in the clinical management of hypereosinophilia. We describe the case of a patient with very severe eosinophilia, in whom antihistamines proved to be effective and safe in contributing to the eosinophil count normalization, thus avoiding the use of steroids until the hypothesis of an underlying neoplastic disorder was reasonably excluded.
Keywords: hypereosinophilia; allergy; antihistamines; corticosteroids hypereosinophilia; allergy; antihistamines; corticosteroids

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MDPI and ACS Style

Vallero, S.; Mondino, A.; Farinasso, L.; Ansaldi, G.; Davitto, M.; Ramenghi, U. Successful Use of Antihistamines in Severe Hypereosinophilia. Pediatr. Rep. 2012, 4, e26. https://doi.org/10.4081/pr.2012.e26

AMA Style

Vallero S, Mondino A, Farinasso L, Ansaldi G, Davitto M, Ramenghi U. Successful Use of Antihistamines in Severe Hypereosinophilia. Pediatric Reports. 2012; 4(3):e26. https://doi.org/10.4081/pr.2012.e26

Chicago/Turabian Style

Vallero, Stefano, Anna Mondino, Loredana Farinasso, Giulia Ansaldi, Mirella Davitto, and Ugo Ramenghi. 2012. "Successful Use of Antihistamines in Severe Hypereosinophilia" Pediatric Reports 4, no. 3: e26. https://doi.org/10.4081/pr.2012.e26

APA Style

Vallero, S., Mondino, A., Farinasso, L., Ansaldi, G., Davitto, M., & Ramenghi, U. (2012). Successful Use of Antihistamines in Severe Hypereosinophilia. Pediatric Reports, 4(3), e26. https://doi.org/10.4081/pr.2012.e26

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