Characterization of Disease Patterns in Children with Intracranial Abscesses for Enhanced Clinical Decision-Making
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patient Selection
2.2. MRI
2.3. Statistics
3. Results
3.1. Epidemiology
3.2. Clinical Symptoms
3.3. Treatment
3.4. Etiology
3.5. Statistical Feature Correlation Analysis
3.6. Recommendations for Clinical Decision-Making
4. Discussion
4.1. Coherent Clinical Presentation of Children with Intracranial Abscesses with a Streptococcal and Anaerobic Pathogen Spectrum
4.2. Sinusitis as the Primary Cause of Intracranial Abscesses in Children: Successful Outcomes with Neurosurgical Craniotomy and Antibiotic Treatment Resulting in No Fatalities
4.3. Feature Analysis Reveals Clinical Feature Combinations to Be Considered for Early Diagnostics and Treatment
4.4. Decreased Overall Transmission of Respiratory Pathogens During COVID-19 Pandemic Maybe Led to a Shift in Incidence and a Seasonal Increase in Intracerebral Abscesses in Children Due to a Catch-Up Effect
4.5. Close Follow-Up Examinations for Children with Neurological Deficits After Early Intervention of Intracranial Abscesses May Require an Individualized Rehabilitation Plan to Improve Outcomes
4.6. Strengths and Limitations
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Middelkamp, M.; Kania, M.M.; Groth, F.S.; Ricklefs, F.L.; Dührsen, L. Characterization of Disease Patterns in Children with Intracranial Abscesses for Enhanced Clinical Decision-Making. Pediatr. Rep. 2024, 16, 1001-1013. https://doi.org/10.3390/pediatric16040085
Middelkamp M, Kania MM, Groth FS, Ricklefs FL, Dührsen L. Characterization of Disease Patterns in Children with Intracranial Abscesses for Enhanced Clinical Decision-Making. Pediatric Reports. 2024; 16(4):1001-1013. https://doi.org/10.3390/pediatric16040085
Chicago/Turabian StyleMiddelkamp, Maximilian, Marcus M. Kania, Friederike S. Groth, Franz L. Ricklefs, and Lasse Dührsen. 2024. "Characterization of Disease Patterns in Children with Intracranial Abscesses for Enhanced Clinical Decision-Making" Pediatric Reports 16, no. 4: 1001-1013. https://doi.org/10.3390/pediatric16040085
APA StyleMiddelkamp, M., Kania, M. M., Groth, F. S., Ricklefs, F. L., & Dührsen, L. (2024). Characterization of Disease Patterns in Children with Intracranial Abscesses for Enhanced Clinical Decision-Making. Pediatric Reports, 16(4), 1001-1013. https://doi.org/10.3390/pediatric16040085