Multisystemic Inflammatory Syndrome Temporally Associated with COVID-19 in a Regional Pediatric Hospital from México
Abstract
1. Introduction
2. Materials and Methods
Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Symptoms | Frequency (%) |
---|---|
Duration of fever (days) | 4 (min. 3, max. 5) |
Diarrhea | 30 (57.7) |
Abdominal pain | 40 (76.9) |
Emesis | 36 (69.2) |
Cutaneous rash | 38 (73) |
Conjunctivitis | 39 (75) |
Cleft lips/strawberry tongue | 35 (67.3) |
Lymphadenopathy | 26 (50) |
Limb edema | 28 (54.9) |
Headache | 15 (28.8) |
Mental alteration/Irritability | 15 (28.8) |
Somnolence | 8 (15.4) |
Test | Value | Reference Range |
---|---|---|
C-Reactive protein (mg/dL) | 18.1 (6.3–26.5) | 0–5 mg/L |
Procalcitonin (ng/mL) | 2.7 (0.8–9) | <0.1 ng/mL |
Erythrocyte sedimentation rate (mm/h) | 40 ± 15.3 | 0–10 mm/h |
D-dimer | 2974 (1457.7–6074) | <0.5 mg/mL |
Ferritin | 245.7 (175.7–463) | 10–200 ng/mL |
Platelets | 184 (104.5–303) | 150–400 × 109 cells/L |
Lymphocytes | 1230 (907–2943) | 3–9.5 × 103 cells/μL |
Sodium | 135 ± 4.9 | (135–145 mEq/L) |
Outcomes | Frequency (%) |
---|---|
General findings in PICU | |
Shock | 12 (23.1) |
Gastrointestinal Bleeding | 1 (1.9) |
Acute Kidney Injury | 8 (15.4) |
Vasopressor support | |
Norepinephrine | 4 (7.7) |
Epinephrine | 1 (1.9) |
Dobutamine | 1 (1.9) |
Norepinephrine + Epinephrine | 2 (3.8) |
Norepinefrine + Dobutamine | 1 (1.9) |
Cardiovascular findings | |
Bilateral opacities | 8 (15.4) |
Acute pericarditis | 4 (7.7) |
Pericardia Effusion | 3 (5.8) |
LV ejection fraction <50% | 1 (1.9) |
Respiratory support | |
Mechanic ventilation | 7 (13.46) |
Oxygen | 3 (5.8) |
Nasal tips | 1 (1.92) |
Pharmacologic therapy | |
Empirical antibiotic treatment | 28 (53.8) |
Ceftriaxone | 26 (50) |
Clindamycin | 8 (15.4) |
Cefepime | 2 (3.85) |
Intravenous immunoglobulin | 51 (98) |
Methyl prednisolone | 50 (96.15) |
Acetylsalicylic acid | 46 (88.4) |
Antiviral treatment | 4 (7.7) |
Oseltamivir | 2 (3.9) |
Acyclovir | 2 (3.9) |
Mortality | 2 (3.8) |
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Barroso-Santos, J.; Robledo-Martínez, A.I.; Espinosa-Padilla, S.E.; Hurtado del Ángel, R.G.; Arteaga-García, F.; Langarica-Bulos, M.; Madrid-Gómez-Tagle, J.A.; Sánchez-Reyes, B.A.; Hernández-Cadena, S.E.; Suárez-Soto, J.I.; et al. Multisystemic Inflammatory Syndrome Temporally Associated with COVID-19 in a Regional Pediatric Hospital from México. Pediatr. Rep. 2023, 15, 341-348. https://doi.org/10.3390/pediatric15020030
Barroso-Santos J, Robledo-Martínez AI, Espinosa-Padilla SE, Hurtado del Ángel RG, Arteaga-García F, Langarica-Bulos M, Madrid-Gómez-Tagle JA, Sánchez-Reyes BA, Hernández-Cadena SE, Suárez-Soto JI, et al. Multisystemic Inflammatory Syndrome Temporally Associated with COVID-19 in a Regional Pediatric Hospital from México. Pediatric Reports. 2023; 15(2):341-348. https://doi.org/10.3390/pediatric15020030
Chicago/Turabian StyleBarroso-Santos, Joel, Angelina Ingrid Robledo-Martínez, Sara Elva Espinosa-Padilla, Rubén Genaro Hurtado del Ángel, Felipe Arteaga-García, Mónica Langarica-Bulos, José Antonio Madrid-Gómez-Tagle, Beatriz Adriana Sánchez-Reyes, Sarai Eunice Hernández-Cadena, Jorge Iván Suárez-Soto, and et al. 2023. "Multisystemic Inflammatory Syndrome Temporally Associated with COVID-19 in a Regional Pediatric Hospital from México" Pediatric Reports 15, no. 2: 341-348. https://doi.org/10.3390/pediatric15020030
APA StyleBarroso-Santos, J., Robledo-Martínez, A. I., Espinosa-Padilla, S. E., Hurtado del Ángel, R. G., Arteaga-García, F., Langarica-Bulos, M., Madrid-Gómez-Tagle, J. A., Sánchez-Reyes, B. A., Hernández-Cadena, S. E., Suárez-Soto, J. I., Delgado-Amézquita, C., Godínez-Hernández, B., Otamendi-Canales, O., & Jiménez-Osorio, A. S. (2023). Multisystemic Inflammatory Syndrome Temporally Associated with COVID-19 in a Regional Pediatric Hospital from México. Pediatric Reports, 15(2), 341-348. https://doi.org/10.3390/pediatric15020030