- Case Report
Sildenafil and bosentan plasma concentrations in a human immunodeficiency virus-infected patient with pulmonary arterial hypertension treated with ritonavir-boosted protease inhibitor
- Pierangelo Chinello,
- Stefania Cicalini,
- Simona Pichini,
- Roberta Pacifici,
- Massimo Tempestilli,
- Maria P. Cicini,
- Leopoldo P. Pucillo and
- Nicola Petrosillo
Sildenafil and bosentan are increasingly used for the treatment of pulmonary arterial hypertension (PAH) in HIV-infected patients. However, concerns exist about pharmacokinetic interactions among sildenafil, bosentan and antiretroviral drugs, includi...

