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Infectious Disease Reports
Volume 4
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10.4081/idr.2012.e17
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Infectious Disease Reports is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Article

Rubella Antibody Screening during Pregnancy in an Urban Area of Northern Italy

by
Massimo De Paschale
1,*,
Maria Teresa Manco
1,
Alessia Paganini
1,
Carlo Agrappi
1,
Paola Mirri
1,
Gabriella Cucchi
1,
Barbara Saccani
2,
Alberto Flores D’Arcais
2 and
Pierangelo Clerici
1
1
Microbiology Unit, Hospital of Legnano, Milan, Italy
2
Pediatric and Neonatal Unit, Hospital of Legnano, Milan, Italy
*
Author to whom correspondence should be addressed.
Infect. Dis. Rep. 2012, 4(1), e17; https://doi.org/10.4081/idr.2012.e17
Submission received: 15 September 2011 / Revised: 16 November 2011 / Accepted: 27 December 2011 / Published: 22 February 2012

Abstract

Various countries have implemented anti-rubella vaccination campaigns with the main aim of preventing congenital infection. In 2003, Italy joined the European WHO programme for the elimination of congenital rubella and issued a special healthcare plan, one of the objectives of which was to reduce the proportion of rubella-susceptible pregnant women to less than 5% by 2005. The aim of this study was to determine the percentage of seronegative pregnant women after the implementation of this plan. Anti-rubella IgG and IgM antibodies were sought in 2385 pregnant women who attended our hospital for serological screening between 1 July 2008 and 30 June 2010. They included 750 women of foreign origin (31.4%). Eight percent of the women were anti-rubella seronegative: 6.2% of the Italians and 11.7% of the non-Italians. Among the women of foreign origin, the percentage of seronegativity ranged from 5.6% of those coming from Eastern Europe to 17.7% of those coming from Latin America. The level of seropositivity among women of Italian origin is high, although the objective of ensuring less than 5% of susceptible pregnant women has not yet been quite reached in our area. However, particular attention needs to be given to women coming from geographical areas characterised by different epidemiologies and vaccination strategies because the percentage of seronegativity is in some cases double that of Italian women.
Keywords: Antibodies; pregnancy; screening; rubella; vaccination Antibodies; pregnancy; screening; rubella; vaccination

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MDPI and ACS Style

De Paschale, M.; Manco, M.T.; Paganini, A.; Agrappi, C.; Mirri, P.; Cucchi, G.; Saccani, B.; Flores D’Arcais, A.; Clerici, P. Rubella Antibody Screening during Pregnancy in an Urban Area of Northern Italy. Infect. Dis. Rep. 2012, 4, e17. https://doi.org/10.4081/idr.2012.e17

AMA Style

De Paschale M, Manco MT, Paganini A, Agrappi C, Mirri P, Cucchi G, Saccani B, Flores D’Arcais A, Clerici P. Rubella Antibody Screening during Pregnancy in an Urban Area of Northern Italy. Infectious Disease Reports. 2012; 4(1):e17. https://doi.org/10.4081/idr.2012.e17

Chicago/Turabian Style

De Paschale, Massimo, Maria Teresa Manco, Alessia Paganini, Carlo Agrappi, Paola Mirri, Gabriella Cucchi, Barbara Saccani, Alberto Flores D’Arcais, and Pierangelo Clerici. 2012. "Rubella Antibody Screening during Pregnancy in an Urban Area of Northern Italy" Infectious Disease Reports 4, no. 1: e17. https://doi.org/10.4081/idr.2012.e17

APA Style

De Paschale, M., Manco, M. T., Paganini, A., Agrappi, C., Mirri, P., Cucchi, G., Saccani, B., Flores D’Arcais, A., & Clerici, P. (2012). Rubella Antibody Screening during Pregnancy in an Urban Area of Northern Italy. Infectious Disease Reports, 4(1), e17. https://doi.org/10.4081/idr.2012.e17

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