Lyme Disease and Associated NMDAR Encephalitis: A Case Report and Literature Review
Abstract
1. Introduction
2. Case Presentation
3. Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Time since First Hospitalization | Blood Serum | Cerebrospinal Fluid | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Leukocytes, 109/L; CRP g/L | Infective | Autoimmune Markers | Tumor Markers | Protein, g/L | Cells, uL | Agranulocytes, % | Infective | Autoimmune | Tumor Markers | |
Day of hospitalization | 13.3; 5.14 | - | - | - | 1.924 | 79 | 85 | - | - | - |
Day 2 | 6.8; 37.35 | - | - | - | - | - | - | |||
Day 3 | - | - | - | 1.658 | 51 | 90 | - | - | - | |
Day 6 | 8.4; 22.90 | Positive B. burgdorferi AI | - | - | - | - | - | Positive B. burgdorferi AI | - | - |
Day 14 | - | Positive anti-NMDAR Abs | Positive anti-recoverin Abs | 1.838 | 68 | 93 | - | Positive anti-NMDAR Abs | Positive anti-recoverin Abs | |
Day 21 | - | - | - | 0.522 | 91 | 97 | - | - | - | |
Day 57 | 7.3; <4.00 | - | - | - | 0.655 | 8 | 88 | - | Negative anti-NMDAR Abs | Positive anti-recoverin Abs |
Day 340 | 7.1; <4.00 | - | Negative anti-NMDAR Abs | Weak, positive anti-recoverin Abs | 0.520 | 0 | 0 | - | Negative anti-NMDAR Abs | Weak, positive anti-recoverin Abs |
Time since First Hospitalization | Blood Serum | Cerebrospinal Fluid | Antibody Index | |||
IgM (Immunoblot) | IgG (ELISA) | IgG (Immunoblot) | IgM (ELISA) | IgG (ELISA) | Positive 3.58 | |
Day 6 | Positive, 9 | Positive, 169 AU/mL | Positive, 12 | Positive, 8.9 AU/mL | Positive, 172.6 AU/mL |
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Predkele, N.; Mednieks, J. Lyme Disease and Associated NMDAR Encephalitis: A Case Report and Literature Review. Neurol. Int. 2021, 13, 487-496. https://doi.org/10.3390/neurolint13040048
Predkele N, Mednieks J. Lyme Disease and Associated NMDAR Encephalitis: A Case Report and Literature Review. Neurology International. 2021; 13(4):487-496. https://doi.org/10.3390/neurolint13040048
Chicago/Turabian StylePredkele, Natalja, and Jānis Mednieks. 2021. "Lyme Disease and Associated NMDAR Encephalitis: A Case Report and Literature Review" Neurology International 13, no. 4: 487-496. https://doi.org/10.3390/neurolint13040048
APA StylePredkele, N., & Mednieks, J. (2021). Lyme Disease and Associated NMDAR Encephalitis: A Case Report and Literature Review. Neurology International, 13(4), 487-496. https://doi.org/10.3390/neurolint13040048