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Case Report

Ranolazine Treatment for Refractory Angina in a Patient with Hutchinson-Gilford Progeria Syndrome and End Stage Aortic Stenosis

by
Giuseppe Limongelli
1,2,
Emanuele Monda
1,*,
Giovanbattista Capozzi
1,
Martina Caiazza
1 and
Maria Giovanna Russo
1
1
Unit of Pediatric Cardiology, Department of Translational Sciences, Luigi Vanvitelli University, AORN Colli, Monaldi Hospital, Naples, Italy
2
Institute of Cardiovascular Sciences, University College of London, UK
*
Author to whom correspondence should be addressed.
Cardiogenetics 2019, 9(1), 14-15; https://doi.org/10.4081/cardiogenetics.2019.8609
Submission received: 7 October 2019 / Revised: 16 December 2019 / Accepted: 4 January 2020 / Published: 30 January 2020

Abstract

Management of symptoms in patients with inoperable aortic stenosis is often hard in clinical practice. We report a case of a patient with Hutchinson-Gilford progeria syndrome and end-stage aortic stenosis, considered not suitable for surgical or percutaneous approach, to whom the administration of ranolazine resulted in a considerable improvement of angina, refractory to other treatments.
Keywords: Hutchinson-Gilford progeria syndrome; aortic stenosis; ranolazine Hutchinson-Gilford progeria syndrome; aortic stenosis; ranolazine

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MDPI and ACS Style

Limongelli, G.; Monda, E.; Capozzi, G.; Caiazza, M.; Russo, M.G. Ranolazine Treatment for Refractory Angina in a Patient with Hutchinson-Gilford Progeria Syndrome and End Stage Aortic Stenosis. Cardiogenetics 2019, 9, 14-15. https://doi.org/10.4081/cardiogenetics.2019.8609

AMA Style

Limongelli G, Monda E, Capozzi G, Caiazza M, Russo MG. Ranolazine Treatment for Refractory Angina in a Patient with Hutchinson-Gilford Progeria Syndrome and End Stage Aortic Stenosis. Cardiogenetics. 2019; 9(1):14-15. https://doi.org/10.4081/cardiogenetics.2019.8609

Chicago/Turabian Style

Limongelli, Giuseppe, Emanuele Monda, Giovanbattista Capozzi, Martina Caiazza, and Maria Giovanna Russo. 2019. "Ranolazine Treatment for Refractory Angina in a Patient with Hutchinson-Gilford Progeria Syndrome and End Stage Aortic Stenosis" Cardiogenetics 9, no. 1: 14-15. https://doi.org/10.4081/cardiogenetics.2019.8609

APA Style

Limongelli, G., Monda, E., Capozzi, G., Caiazza, M., & Russo, M. G. (2019). Ranolazine Treatment for Refractory Angina in a Patient with Hutchinson-Gilford Progeria Syndrome and End Stage Aortic Stenosis. Cardiogenetics, 9(1), 14-15. https://doi.org/10.4081/cardiogenetics.2019.8609

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