Use of Plant Extracts in Polymeric Scaffolds in the Regeneration of Mandibular Injuries
Abstract
:1. Introduction
2. Materials and Methods
2.1. Process for Obtaining Scaffolds
2.1.1. Materials
2.1.2. Scaffold Preparation
2.2. Characterization Process of the Scaffolds
2.2.1. Differential Scanning Calorimetry (DSC)
2.2.2. Fourier Transform Infrared Spectroscopy (FT-IR)
2.2.3. Analysis of Scaffolds with Scanning Electron Microscopy (SEM)
2.2.4. Porosity
2.2.5. Absorption in Phosphate Buffered Saline (PBS)
2.3. Experimental Design
2.4. Surgical Technique for Creating the Mandibular Defect
3. Results and Discussion
3.1. Physical–Chemical Analysis of the Scaffolds Used in the Experiment
3.2. Clinical Analysis of Scaffold Grafting in the Repair of Mandibular Lesions in Rats
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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G1-C | G2-CCJ | G3-CHER |
---|---|---|
17.17 ± 2.68 a | 27.45 ± 1.65 b | 34.07 ± 0.64 c |
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de Oliveira, B.E.G.; Maia, F.L.M.; Massimino, L.C.; Garcia, C.F.; Plepis, A.M.d.G.; Martins, V.d.C.A.; Reis, C.H.B.; Silva, V.R.; Bezerra, A.A.; Pauris, C.C.; et al. Use of Plant Extracts in Polymeric Scaffolds in the Regeneration of Mandibular Injuries. Pharmaceutics 2024, 16, 491. https://doi.org/10.3390/pharmaceutics16040491
de Oliveira BEG, Maia FLM, Massimino LC, Garcia CF, Plepis AMdG, Martins VdCA, Reis CHB, Silva VR, Bezerra AA, Pauris CC, et al. Use of Plant Extracts in Polymeric Scaffolds in the Regeneration of Mandibular Injuries. Pharmaceutics. 2024; 16(4):491. https://doi.org/10.3390/pharmaceutics16040491
Chicago/Turabian Stylede Oliveira, Bruna Eduarda Gandra, Fernanda Latorre Melgaço Maia, Lívia Contini Massimino, Claudio Fernandes Garcia, Ana Maria de Guzzi Plepis, Virgínia da Conceição Amaro Martins, Carlos Henrique Bertoni Reis, Vinícius Rodrigues Silva, Andre Alves Bezerra, Carolina Chen Pauris, and et al. 2024. "Use of Plant Extracts in Polymeric Scaffolds in the Regeneration of Mandibular Injuries" Pharmaceutics 16, no. 4: 491. https://doi.org/10.3390/pharmaceutics16040491