RETRACTED: Alhakamy et al. Optimized Icariin Phytosomes Exhibit Enhanced Cytotoxicity and Apoptosis-Inducing Activities in Ovarian Cancer Cells. Pharmaceutics 2020, 12, 346
by
, , , , , , , ,
Nabil A. Alhakamy
1,2,3,4,
Usama A. Fahmy
1,*
,
Shaimaa M. Badr-Eldin
1,5,
Osama A. A. Ahmed
1,
Hani Z. Asfour
6,
Hibah M. Aldawsari
1,
Mardi M. Algandaby
7,
Basma G. Eid
8,
Ashraf B. Abdel-Naim
8,
Zuhier A. Awan
9,
Nabil K. Alruwaili
10 and
Amir I. Mohamed
11 1
Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
2
Center of Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah 21589, Saudi Arabia
3
King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia
4
Advanced Drug Delivery Research Group, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
5
Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt
6
Department of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia
7
Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah 21579, Saudi Arabia
8
Department of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
9
Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia
10
Department of Pharmaceutics, Faculty of Pharmacy, Jouf University, Skaka 2014, Saudi Arabia
11
Department of Pharmaceutics and Industrial Pharmacy, Military Medical Academy, Cairo 11757, Egypt
*
Author to whom correspondence should be addressed.
Pharmaceutics 2024, 16(2), 194; https://doi.org/10.3390/pharmaceutics16020194
Submission received: 15 January 2024
/
Accepted: 16 January 2024
/
Published: 30 January 2024
The journal retracts the article, “Optimized Icariin Phytosomes Exhibit Enhanced Cytotoxicity and Apoptosis-Inducing Activities in Ovarian Cancer Cells” [1] cited above.
Following publication, concerns were brought to the attention of the publisher regarding duplicated images across other publications [2,3,4,5,6,7], representing different experimental conditions.
Adhering to our complaint procedure, an investigation was conducted that confirmed that Figure S2 of [1] is a duplicate of Figure 8 of [2], Figure 7 of [3], Figure 7 of [4], Figure 7 of [5], Figure 7 of [6] and Figure 4 of [7].
While the authors fully cooperated with the Editorial Office during the investigation, they were unable to satisfactorily explain the overlap of figures presenting different experimental conditions and meet the required quality standards of original images in order to consider a correction as per the journal’s original image requirements policy (https://www.mdpi.com/journal/pharmaceutics/instruc-tions#oriimages). As a result, the Editorial Board and Editor-in-Chief were unable to confirm the reliability of the findings and subsequently decided to retract this paper as per MDPI’s retraction policy (https://www.mdpi.com/ethics#_bookmark30).
This retraction was approved by the Editor-in-Chief of the journal Pharmaceutics.
The authors did not comment on this retraction.
References
- Alhakamy, N.A.; Fahmy, U.A.; Badr-Eldin, S.M.; Ahmed, O.A.A.; Asfour, H.Z.; Aldawsari, H.M.; Algandaby, M.M.; Eid, B.G.; Abdel-Naim, A.B.; Awan, Z.A.; et al. RETRACTED: Optimized Icariin Phytosomes Exhibit Enhanced Cytotoxicity and Apoptosis-Inducing Activities in Ovarian Cancer Cells. Pharmaceutics 2020, 12, 346. [Google Scholar] [CrossRef] [PubMed]
- Awan, Z.A.; Fahmy, U.A.; Badr-Eldin, S.M.; Ibrahim, T.S.; Asfour, H.Z.; Al-Rabia, M.W.; Alfarsi, A.; Alhakamy, N.A.; Abdulaal, W.H.; Al Sadoun, H.; et al. The Enhanced Cytotoxic and Pro-Apoptotic Effects of Optimized Simvastatin-Loaded Emulsomes on MCF-7 Breast Cancer Cells. Pharmaceutics 2020, 12, 597. [Google Scholar] [CrossRef] [PubMed]
- Alhakamy, N.A.; Badr-Eldin, S.M.; Ahmed, O.A.A.; Asfour, H.Z.; Aldawsari, H.M.; Algandaby, M.M.; Eid, B.G.; Abdel-Naim, A.B.; Awan, Z.A.; Alghaith, A.F.; et al. Piceatannol-Loaded Emulsomes Exhibit Enhanced Cytostatic and Apoptotic Activities in Colon Cancer Cells. Antioxidants 2020, 9, 419. [Google Scholar] [CrossRef] [PubMed]
- Alhakamy, N.A.; Badr-Eldin, S.M.; Aldawsari, H.M.; Alfarsi, A.; Neamatallah, T.; Okbazghi, S.Z.; Fahmy, U.A.; Ahmad, O.A.; Eid, B.G.; Mahdi, W.A.; et al. Retraction Note: Fluvastatin-Loaded Emulsomes Exhibit Improved Cytotoxic and Apoptosis in Prostate Cancer Cells. AAPS PharmSciTech 2021, 22, 177. [Google Scholar] [CrossRef] [PubMed]
- Badr-Eldin, S.M.; Aldawsari, H.M.; Ahmed, O.A.; Alhakamy, N.A.; Neamatallah, T.; Okbazghi, S.Z.; Fahmy, U.A. Optimized semisolid self-nanoemulsifying system based on glyceryl behenate: A potential nanoplatform for enhancing antitumor activity of raloxifene hydrochloride in MCF-7 human breast cancer cells. Int. J. Pharm. 2021, 600, 120493. [Google Scholar] [CrossRef] [PubMed]
- Alhakamy, N.A.; Badr-Eldin, S.M.; Fahmy, U.A.; Alruwaili, N.K.; Awan, Z.A.; Caruso, G.; Alfaleh, M.A.; Alaofi, A.L.; Arif, F.O.; Ahmed, O.A.A.; et al. Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells. Pharmaceutics 2020, 12, 761. [Google Scholar] [CrossRef] [PubMed]
- Aldawsari, H.M.; Ahmed, O.A.A.; Alhakamy, N.A.; Neamatallah, T.; Fahmy, U.A.; Badr-Eldin, S.M. Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment. Pharmaceutics 2021, 13, 783. [Google Scholar] [CrossRef] [PubMed]
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MDPI and ACS Style
Alhakamy, N.A.; Fahmy, U.A.; Badr-Eldin, S.M.; Ahmed, O.A.A.; Asfour, H.Z.; Aldawsari, H.M.; Algandaby, M.M.; Eid, B.G.; Abdel-Naim, A.B.; Awan, Z.A.; et al. RETRACTED: Alhakamy et al. Optimized Icariin Phytosomes Exhibit Enhanced Cytotoxicity and Apoptosis-Inducing Activities in Ovarian Cancer Cells. Pharmaceutics 2020, 12, 346. Pharmaceutics 2024, 16, 194. https://doi.org/10.3390/pharmaceutics16020194
AMA Style
Alhakamy NA, Fahmy UA, Badr-Eldin SM, Ahmed OAA, Asfour HZ, Aldawsari HM, Algandaby MM, Eid BG, Abdel-Naim AB, Awan ZA, et al. RETRACTED: Alhakamy et al. Optimized Icariin Phytosomes Exhibit Enhanced Cytotoxicity and Apoptosis-Inducing Activities in Ovarian Cancer Cells. Pharmaceutics 2020, 12, 346. Pharmaceutics. 2024; 16(2):194. https://doi.org/10.3390/pharmaceutics16020194
Chicago/Turabian StyleAlhakamy, Nabil A., Usama A. Fahmy, Shaimaa M. Badr-Eldin, Osama A. A. Ahmed, Hani Z. Asfour, Hibah M. Aldawsari, Mardi M. Algandaby, Basma G. Eid, Ashraf B. Abdel-Naim, Zuhier A. Awan, and et al. 2024. "RETRACTED: Alhakamy et al. Optimized Icariin Phytosomes Exhibit Enhanced Cytotoxicity and Apoptosis-Inducing Activities in Ovarian Cancer Cells. Pharmaceutics 2020, 12, 346" Pharmaceutics 16, no. 2: 194. https://doi.org/10.3390/pharmaceutics16020194
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