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Open AccessReview

Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations

1
Department of Engineering for Innovation, University of Salento, via Monteroni, 73100 Lecce, Italy
2
CNR Nanotec, Institute of Nanotechnology, via Monteroni, 73100 Lecce, Italy
3
Department of Chemistry “Ugo Schiff”, University of Florence, via della Lastruccia 13, Sesto Fiorentino, 50019 Firenze, Italy
*
Author to whom correspondence should be addressed.
Pharmaceutics 2019, 11(10), 505; https://doi.org/10.3390/pharmaceutics11100505
Received: 7 August 2019 / Revised: 26 September 2019 / Accepted: 27 September 2019 / Published: 1 October 2019
Reactive oxygen and nitrogen species (RONS) are produced endogenously in our body, or introduced through external factors, such as pollution, cigarette smoke, and excessive sunlight exposure. In normal conditions, there is a physiological balance between pro-oxidant species and antioxidant molecules that are able to counteract the detrimental effect of the former. Nevertheless, when this homeostasis is disrupted, the resulting oxidative stress can lead to several pathological conditions, from inflammation to cancer and neurodegenerative diseases. In this review, we report on the recent developments of different polymeric formulations that are able to reduce the oxidative stress, from natural extracts, to films and hydrogels, and finally to nanoparticles (NPs). View Full-Text
Keywords: antioxidant; radicals; ROS; polymer; chitosan; extract; film; hydrogel; nanoparticle antioxidant; radicals; ROS; polymer; chitosan; extract; film; hydrogel; nanoparticle
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MDPI and ACS Style

Zafar, M.S.; Quarta, A.; Marradi, M.; Ragusa, A. Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations. Pharmaceutics 2019, 11, 505.

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